Thioxanthone , >98.0% , 492-22-8

Synonym(s):
9-Oxothioxanthene;Thioxanthen-9-one;Thioxanthone

CAS NO.：492-22-8

Empirical Formula: C13H8OS

Molecular Weight: 212.27

MDL number: MFCD00005066

EINECS: 207-749-4

PRODUCT Properties

• Melting point: 210-213 °C(lit.)
• Boiling point: 371-373 °C715 mm Hg(lit.)
• Density: 1.2247 (rough estimate)
• refractive index: 1.5700 (estimate)
• Flash point: 371-373°C/715mm
• storage temp.: 2-8°C
• solubility: Chloroform (Slightly), Methanol (Slightly)
• color: Pale Yellow to Light Yellow
• Water Solubility: practically insoluble
• Merck: 14,9369
• BRN: 140978
• Stability: Stable. Incompatible with strong oxidizing agents.
• InChIKey: YRHRIQCWCFGUEQ-UHFFFAOYSA-N
• CAS DataBase Reference: 492-22-8(CAS DataBase Reference)
• NIST Chemistry Reference: Thioxanthone(492-22-8)
• EPA Substance Registry System: Thioxanthone (492-22-8)

Description and Uses

Thioxanthone is a heterocyclic compound that is a sulfur analog of xanthone.
Thioxanthone can be prepared by the reaction of diphenyl sulfide with phosgene in the presence of catalytic aluminium chloride. This synthesis can be seen as a special case of the Friedel-Crafts acylation. The reduction product is thioxanthene.
Thioxanthone dissolves in concentrated sulfuric acid to give a yellow colored liquid with intense green fluorescence. A mixture of the thioxanthone derivatives of 2- and 4-isopropylthioxanthone (ITX) is used in the printing industry. Pharmaceutical drugs that are derivatives of thioxanthone include hycanthone and lucanthone.

Thioxanthen-9-one is a reagent and a starting material for the synthesis of Metixene Hydrochloride. It is also used for highly functional group tolerant and chemoselective oxidation of aromatic or aliphatic sulfides to sulfoxides with hydrogen peroxide.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302-H315-H319-H335
• Precautionary statements: P261-P305+P351+P338
• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 22-24/25-37/39-26
• WGK Germany: 3
• Hazard Note: Irritant
• TSCA: Yes
• HS Code: 29349990