Home Categories Organic Chemistry Triisopropylsilyl Trifluoromethanesulfonate
A7876112

Triisopropylsilyl Trifluoromethanesulfonate , 98% , 80522-42-5

Synonym(s):
TIPS triflate;Trifluoromethanesulfonic acid triisopropylsilyl ester;Triisopropylsilyl triflate

CAS NO.:80522-42-5

Empirical Formula: C10H21F3O3SSi

Molecular Weight: 306.42

MDL number: MFCD00009913

EINECS: 638-988-6

Pack Size Price Stock Quantity
5G RMB52.00 In Stock
10g RMB79.20 In Stock
25G RMB150.40 In Stock
100g RMB568.80 In Stock
500g RMB2648.80 In Stock
others     Enquire
Update time: 2022-07-08

PRODUCT Properties

Boiling point: 45-46 °C/0.03 mmHg
Density  1.14 g/mL at 25 °C (lit.)
refractive index  n20/D 1.415(lit.)
Flash point: 213 °F
storage temp.  under inert gas (nitrogen or Argon) at 2-8°C
solubility  Miscible with chloroform and ethyl acetate.
form  Liquid
Specific Gravity 1.14
color  Clear light brown to orange-brown
Sensitive  Moisture Sensitive
Hydrolytic Sensitivity 8: reacts rapidly with moisture, water, protic solvents
BRN  3591541
InChI InChI=1S/C10H21F3O3SSi/c1-7(2)18(8(3)4,9(5)6)16-17(14,15)10(11,12)13/h7-9H,1-6H3
InChIKey LHJCZOXMCGQVDQ-UHFFFAOYSA-N
SMILES C(F)(F)(F)S(O[Si](C(C)C)(C(C)C)C(C)C)(=O)=O
CAS DataBase Reference 80522-42-5(CAS DataBase Reference)

Description and Uses

Triisopropylsilyl trifluoromethanesulfonate is used as a reagent for the introduction of triisopropylsilyl(TIPS) group in organic synthesis. It is involved in the synthesis of 2-substituted benzothiopyran-4-ones and silyloxy acetylenes. As a protecting group in organic synthesis, it is utilized especially for the protection of primary amines. Furthermore, it plays an important role in Takahashi Taxol total synthesis or for chemical glycosylation reactions.

Safety

Symbol(GHS) 
GHS05
Signal word  Danger
Hazard statements  H314
Precautionary statements  P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363-P405
Hazard Codes  C
Risk Statements  34
Safety Statements  26-36/37/39-45-28A-27
RIDADR  UN 3265 8/PG 2
WGK Germany  3
3-10-21
TSCA  No
HazardClass  8
PackingGroup  II
HS Code  29319090

RELATED PRODUCTS