A7876112
Triisopropylsilyl Trifluoromethanesulfonate , 98% , 80522-42-5
Synonym(s):
TIPS triflate;Trifluoromethanesulfonic acid triisopropylsilyl ester;Triisopropylsilyl triflate
CAS NO.:80522-42-5
Empirical Formula: C10H21F3O3SSi
Molecular Weight: 306.42
MDL number: MFCD00009913
EINECS: 638-988-6
Pack Size | Price | Stock | Quantity |
5G | RMB52.00 | In Stock |
|
10g | RMB79.20 | In Stock |
|
25G | RMB150.40 | In Stock |
|
100g | RMB568.80 | In Stock |
|
500g | RMB2648.80 | In Stock |
|
others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
Boiling point: | 45-46 °C/0.03 mmHg |
Density | 1.14 g/mL at 25 °C (lit.) |
refractive index | n |
Flash point: | 213 °F |
storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
solubility | Miscible with chloroform and ethyl acetate. |
form | Liquid |
Specific Gravity | 1.14 |
color | Clear light brown to orange-brown |
Sensitive | Moisture Sensitive |
Hydrolytic Sensitivity | 8: reacts rapidly with moisture, water, protic solvents |
BRN | 3591541 |
InChI | InChI=1S/C10H21F3O3SSi/c1-7(2)18(8(3)4,9(5)6)16-17(14,15)10(11,12)13/h7-9H,1-6H3 |
InChIKey | LHJCZOXMCGQVDQ-UHFFFAOYSA-N |
SMILES | C(F)(F)(F)S(O[Si](C(C)C)(C(C)C)C(C)C)(=O)=O |
CAS DataBase Reference | 80522-42-5(CAS DataBase Reference) |
Description and Uses
Triisopropylsilyl trifluoromethanesulfonate is used as a reagent for the introduction of triisopropylsilyl(TIPS) group in organic synthesis. It is involved in the synthesis of 2-substituted benzothiopyran-4-ones and silyloxy acetylenes. As a protecting group in organic synthesis, it is utilized especially for the protection of primary amines. Furthermore, it plays an important role in Takahashi Taxol total synthesis or for chemical glycosylation reactions.
Safety
Symbol(GHS) | GHS05 |
Signal word | Danger |
Hazard statements | H314 |
Precautionary statements | P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363-P405 |
Hazard Codes | C |
Risk Statements | 34 |
Safety Statements | 26-36/37/39-45-28A-27 |
RIDADR | UN 3265 8/PG 2 |
WGK Germany | 3 |
F | 3-10-21 |
TSCA | No |
HazardClass | 8 |
PackingGroup | II |
HS Code | 29319090 |