Trimethylsilyl Bromoacetate , >97.0%(GC) , 18291-80-0

CAS NO.：18291-80-0

Empirical Formula: C5H11BrO2Si

Molecular Weight: 211.13

MDL number: MFCD00000187

EINECS: 242-165-3

PRODUCT Properties

• Boiling point: 57-58 °C/9 mmHg (lit.)
• Density: 1.284 g/mL at 25 °C (lit.)
• vapor density: >1 (vs air)
• refractive index: n20/D 1.442(lit.)
• Flash point: 83 °F
• storage temp.: Flammables area
• form: clear liquid
• color: Colorless to Light yellow
• Specific Gravity: 1.299
• Hydrolytic Sensitivity: 7: reacts slowly with moisture/water
• Sensitive: Moisture Sensitive
• BRN: 1927560

Description and Uses

Trimethylsilyl bromoacetate has been used:

• in the preparation of new imidazolium salts functionalized with the trimethylsilyl ester group
• as alkylating agent in the synthesis of succinate fragment of pantocin B (antibiotic natural product)
• in the synthesis of taxol derivatives tethered at C2′ and C-7 to glutamate and folate

Safety

• Symbol(GHS): GHS02,GHS05
• Signal word: Danger
• Hazard statements: H226-H314
• Precautionary statements: P210-P233-P240-P280-P303+P361+P353-P305+P351+P338
• Hazard Codes: C
• Risk Statements: 10-34
• Safety Statements: 26-36/37/39-45
• RIDADR: UN 2920 8/PG 2
• WGK Germany: 3
• F: 10-19-21
• TSCA: No
• HazardClass: 8
• PackingGroup: II
• HS Code: 29310099