Home Categories Organic Chemistry N,N,N′,N′-Tetramethylethylenediamine
A7857212

N,N,N′,N′-Tetramethylethylenediamine , 96% , 110-18-9

Synonym(s):
TMEDA;TEMED;Putrescine;1,4-Diaminobutane;1,4-Butanediamine

CAS NO.:110-18-9

Empirical Formula: C6H16N2

Molecular Weight: 116.2

MDL number: MFCD00008335

EINECS: 203-744-6

Update time: 2022-07-08

PRODUCT Properties

Melting point: −55 °C(lit.)
Boiling point: 120-122 °C(lit.)
Density  0.775 g/mL at 20 °C(lit.)
vapor density  4 (vs air)
vapor pressure  21 hPa (20 °C)
refractive index  n20/D 1.4179(lit.)
Flash point: 50 °F
storage temp.  Store below +30°C.
solubility  H2O: 10 mg/mL at 20 °C, clear, colorless
form  Liquid
pka 10.40, 8.26(at 25℃)
Specific Gravity 0.777 (20/4℃)
color  Clear colorless to slightly yellow
Odor Amine like
PH 8.0-8.5 (0.1g/l, H2O, 20℃)
explosive limit 1-9%(V)
Water Solubility  miscible
Sensitive  Hygroscopic
Merck  14,9134
BRN  1732991
Stability: Stable. Highly flammable. Incompatible with strong oxidizing agents, acids, acid chlorides, acid anhydrides, copper, mercury.
InChIKey DMQSHEKGGUOYJS-UHFFFAOYSA-N
LogP -0.13 at 20.2℃
CAS DataBase Reference 110-18-9(CAS DataBase Reference)
NIST Chemistry Reference 1,2-Ethanediamine, N,N,N',N'-tetramethyl-(110-18-9)
EPA Substance Registry System Tetramethylethylenediamine (110-18-9)

Description and Uses

N,N,N',N'-Tetramethylethylenediamine is used as polymerization accelerator in gel electrophoresis, solvent and oxidizing reagent. It is also used for the separation of proteins or nucleic acids. Further, it is employed as a ligand for metal ions like zinc and copper. It is actively involved in the formation of anionic organometallic complex.

Safety

Symbol(GHS) 
GHS02,GHS05,GHS06
Signal word  Danger
Hazard statements  H225-H301+H331-H314
Precautionary statements  P210-P233-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338
Hazard Codes  F,C,Xi
Risk Statements  11-20/22-34-20/21/22
Safety Statements  16-26-36/37/39-45
RIDADR  UN 2372 3/PG 2
WGK Germany  1
RTECS  KV7175000
3-8-10-34
Autoignition Temperature 145 °C
Hazard Note  Irritant
TSCA  Yes
HazardClass  3
PackingGroup  II
HS Code  29212900
Hazardous Substances Data 110-18-9(Hazardous Substances Data)

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