Home Categories Chemical Reagents Tetraethyl methylenediphosphonate
A7847812

Tetraethyl methylenediphosphonate , ≥98% , 1660-94-2

Synonym(s):
Bis(diethoxyphosphinyl)methane;Methylenediphosphonic acid tetraethylester;NSC 133889

CAS NO.:1660-94-2

Empirical Formula: C9H22O6P2

Molecular Weight: 288.21

MDL number: MFCD00039887

EINECS: 216-764-5

Pack Size Price Stock Quantity
5ML RMB100.00 In Stock
25ML RMB444.00 In Stock
100ML RMB1735.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Boiling point: 171-174 °C11 mm Hg(lit.)
Density  1.16 g/mL at 25 °C(lit.)
refractive index  n20/D 1.442(lit.)
Flash point: >230 °F
storage temp.  Inert atmosphere,Room Temperature
solubility  Chloroform (Sparingly), Methanol (Slightly)
form  Liquid
Specific Gravity 1.160
color  Clear yellow to yellow-brown
Water Solubility  Slightly miscible with water.
BRN  1813241
InChIKey STJWVOQLJPNAQL-UHFFFAOYSA-N
CAS DataBase Reference 1660-94-2(CAS DataBase Reference)
EPA Substance Registry System Phosphonic acid, methylenebis-, tetraethyl ester (1660-94-2)

Description and Uses

Reactant for synthesis of:

  • Dual substrate-site inhibitors of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase
  • Unnatural alpha-amino acid derivatives containing gem-biphosphonates
  • Biphenyl sulfonylamino Me bisphosphonic acids as inhibitors of matrix metalloproteinases and bone resorption
  • Lycopene via Wittig-Horner reaction
  • Alkylaminoethylbisphosphinic acids to target farnesyl diphosphate synthase
  • Aromatic bisphosphonates for use as inhibitors of geranylgeranyl diphosphate synthase

Precursor for synthesis of dendritic polyglycerol anions used toward L-selectin inhibition

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P280g-P305+P351+P338
Hazard Codes  Xi,C
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
RTECS  SZ9150000
Hazard Note  Corrosive
TSCA  Yes
HS Code  29319090
Toxicity mouse,LD50,intravenous,180mg/kg (180mg/kg),U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#03139,

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