Tolterodine tartrate , ≥98% , 124937-52-6

Synonym(s):
E;s (R)-2-[3-[bis(1-methylethyl)-amino]1-phenylpropyl]-4-methylphenol [R-(R*,R*)]2,3dihydroxybutanedioate (1:1) (salt);(R)-Tolterodine L-tartrate;2-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-methyl-phenol tartrate;Detrusitol

CAS NO.：124937-52-6

Empirical Formula: C26H37NO7

Molecular Weight: 475.57

MDL number: MFCD07771985

EINECS: 620-503-4

PRODUCT Properties

• Melting point: 205-210°C
• alpha: 54625 +36.0°
• storage temp.: Sealed in dry,2-8°C
• solubility: Methanol (Sparingly), Water (Slightly)
• pka: 9.87(at 25℃)
• form: Solid
• color: White to Off-White
• BCS Class: 1

Description and Uses

Tolterodine (tartrate) is a competitive antagonist of muscarinic (M) receptors (Ki = 1.4, 2.7, 3.6, 3.1, and 2.2 nM for M1 through M5, respectively). Antagonists of muscarinic receptors, including tolterodine, are effective in treating overactive bladder symptoms.[Cayman Chemical]

Safety

• Symbol(GHS): GHS08,GHS09
• Signal word: Warning
• Hazard statements: H361d-H411
• Precautionary statements: P201-P202-P273-P280-P308+P313-P391
• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 26-37/39
• RIDADR: UN 2811 6.1 / PGIII
• HS Code: 29222990
• Toxicity: LD50 i.v. in male mice: 10-20 mg/kg (Jnsson)