5-(Trifluoromethoxy)isatin , ≥98.0% , 169037-23-4

Synonym(s):
5-(Trifluoromethoxy)indoline-2,3-dione

CAS NO.：169037-23-4

Empirical Formula: C9H4F3NO3

Molecular Weight: 231.13

MDL number: MFCD00192524

EINECS: 1592732-453-0

PRODUCT Properties

• Melting point: 170-172 °C(lit.)
• Density: 1.562±0.06 g/cm3(Predicted)
• storage temp.: Keep in dark place,Sealed in dry,Room Temperature
• pka: 8.49±0.20(Predicted)
• form: powder to crystal
• color: Light yellow to Brown
• Water Solubility: Insoluble in water.

Description and Uses

5-(Trifluoromethoxy)isatin is used as a reactant for preparation of oxindole derivatives as TAk1 kinase inhibitors and of isatin thiosemicarbazones via condensation with thiosemicarbazones as herpes simplex virus (HSV) inhibitors. It is also used as a reactant for synthesis of 3-substituted 2-indolinone RET kinase inhibitors and for preparation of indolone acetamides as antiseizure agents.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P362+P364-P403+P233-P501c
• Hazard Codes: Xi
• Safety Statements: 24/25
• WGK Germany: 3
• Hazard Note: Irritant/Keep Cold
• HS Code: 29339900