Loxapinesuccinate , 10mMinDMSO , 27833-64-3
Synonym(s):
Loxapine succinate salt
CAS NO.:27833-64-3
Empirical Formula: C22H24ClN3O5
Molecular Weight: 445.9
MDL number: MFCD00069298
EINECS: 248-682-0
Pack Size | Price | Stock | Quantity |
1ml | RMB399.20 | In Stock |
|
others | Enquire |
PRODUCT Properties
Melting point: | 150-152°C |
storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
solubility | H2O: soluble |
form | solid |
color | white |
CAS DataBase Reference | 27833-64-3(CAS DataBase Reference) |
Description and Uses
Loxapine was first developed in the late 1960s and was introduced into clinical practice in the following decade. It is used primarily to treat the psychotic symptoms of schizophrenia. It is a member of the dibenzoxazepine class and is structurally related to clozapine. The introduction of newer antipsychotic agents has resulted in the reduced utilization of loxapine over the last few decades.
Loxapine is used to treat and control the psychotic symptoms of both acute and chronic schizophrenia. Other uses include treatment of dementia, anxiety neurosis, hostile/aggressive behavior, and psychotic depression. An inhalation powder of loxapine (Adasuve) was recently approved in the United States and the European Union for the acute management of agitation in patients with bipolar disorder or schizophrenia.
Safety
Symbol(GHS) | GHS07,GHS06 |
Signal word | Danger |
Hazard statements | H301-H319 |
Precautionary statements | P264-P270-P301+P310-P321-P330-P405-P501-P264-P280-P305+P351+P338-P337+P313P |
RIDADR | UN 2811 6.1 / PGII |
WGK Germany | 3 |
RTECS | WM5750000 |
HS Code | 29329990 |