Home Categories Natural Products Kaempferol3-O-β-rutinoside
A7761058

Kaempferol3-O-β-rutinoside , 10mMinDMSO , 17650-84-9

Synonym(s):
3,4′,5,7-Tetrahydroxyflavone 3-rhamnoglucoside;Kaempferol 3-O-β -rutinoside;Nicotiflorin

CAS NO.:17650-84-9

Empirical Formula: C27H30O15

Molecular Weight: 594.52

MDL number: MFCD03427292

Pack Size Price Stock Quantity
1ml RMB559.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 200°C (dec.)
Boiling point: 941.7±65.0 °C(Predicted)
Density  1.76
storage temp.  Inert atmosphere,Store in freezer, under -20°C
solubility  Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form  Solid
pka 6.20±0.40(Predicted)
color  Off-White to Yellow
Stability: Hygroscopic

Description and Uses

Nicotiflorin is a flavonoid that has been found in I. glandulifera and has antioxidant and neuroprotective activities. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) and ABTS radicals with EC50 values of 0.52 and 0.48 mg/ml, respectively, in cell-free assays. Nicotiflorin (1 μM) prevents hydrogen peroxide-induced decreases in tyrosine hydroxylase activity in PC12 cells and cell death in primary rat mesencephalic neurons. It decreases infarct volume by 24.5, 45.8, and 63.2% when administered at doses of 2.5, 5, and 10 mg/kg, respectively, in a rat model of cerebral ischemia-reperfusion injury induced by transient middle central artery occlusion (MCAO).

Kaempferol 3-O-β -Rutinoside is a flavonoid antioxidant compound from Cichorium spinosum L. ecotype plants and also may display anti-diabetic activity. It is a component of many plant species including Helianthemum ruficomum.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P280-P305+P351+P338
Hazard Codes  Xn
Risk Statements  22
Safety Statements  22-45-24/25
WGK Germany  3
HS Code  29389090

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