Marbofloxacin , 2mMinDMSO , 115550-35-1
Synonym(s):
9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-piperazino)-7-oxo-7H-pyrido[1,2,3-ij][1,2,4]benzoxadiazine-6-carboxylic acid;Zeniquin
CAS NO.：115550-35-1
Empirical Formula: C17H19FN4O4
Molecular Weight: 362.36
MDL number: MFCD00864820
EINECS: 640-416-5
| Pack Size | Price | Stock | Quantity |
| 1ml | RMB159.20 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 268-269°C (dec.) |
| Boiling point: | 571℃ |
| Density | 1.55±0.1 g/cm3(Predicted) |
| Flash point: | >110°(230°F) |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | Chloroform (Slightly, Heated) |
| pka | 6.02±0.20(Predicted) |
| form | Solid |
| color | Light Yellow |
| Water Solubility | Soluble in DMSO at 2mg/ml. Soluble in water or ethanol at <1mg/ml |
| Merck | 14,5750 |
| InChI | InChI=1S/C17H19FN4O4/c1-19-3-5-21(6-4-19)14-12(18)7-10-13-16(14)26-9-20(2)22(13)8-11(15(10)23)17(24)25/h7-8H,3-6,9H2,1-2H3,(H,24,25) |
| InChIKey | BPFYOAJNDMUVBL-UHFFFAOYSA-N |
| SMILES | N12C=C(C(O)=O)C(=O)C3=C1C(=C(N1CCN(C)CC1)C(F)=C3)OCN2C |
| CAS DataBase Reference | 115550-35-1(CAS DataBase Reference) |
Description and Uses
Marbofloxacin is a fluoroquinolone antibiotic that is active against P. multocida in vitro (MIC = 0.016 μg/ml). It exhibits broad-spectrum antibacterial activity mediated by the inhibition of DNA gyrase, with MIC values ranging from 0.016 to 0.4 and 0.19 to 1.7 μg/ml against various Gram-negative and Gram-positive bacterial isolates, respectively. In vivo, the administration of marbofloxacin (2 mg/kg, i.m.) after infection prevents the formation of pulmonary lesions in a bovine calf model of M. haemolytica A1 pneumonia. Oral marbofloxacin (2 mg/kg per day) also exhibits antileishmanial activity in a canine model of leishmaniasis, decreasing parasitic load by 72%. Formulations containing marbofloxacin have been used in the veterinary treatment of bacterial infections.
A broad spectrum antibiotic commonly used to target Pseudomonas and Staphylococci species
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H412 |
| Precautionary statements | P273-P501 |
| Hazard Codes | Xi |
| Risk Statements | 52/53-36/37/38 |
| Safety Statements | 61-36-26-60 |
| WGK Germany | 2 |
| RTECS | UU8815140 |
| HS Code | 29349990 |
