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A7744858

LarotrectinibFor , 10mMinDMSO , 1223403-58-4

CAS NO.:1223403-58-4

Empirical Formula: C21H22F2N6O2

Molecular Weight: 428.44

MDL number: MFCD28902192

Pack Size Price Stock Quantity
1ml RMB205.60 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Density  1.55±0.1 g/cm3(Predicted)
storage temp.  RT
solubility  Soluble in DMSO (up to 5 mg/ml).
form  solid
pka 8.41±0.40(Predicted)
color  Yellow
Stability: Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.

Description and Uses

Larotrectinib, also known as LOXO-101 and ARRY-470, is a small molecule that was designed to block the ATP-binding site of the TRKA, TRKB, and TRKC, serving as a highly specific and potent inhibitor of all of the three tropomyosin kinase receptors.

Larotrectinib is a TRK Inhibitor (Tyrosine kinase inhibitor).

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H317
Precautionary statements  P280

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