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A7743758

Emetinedihydrochloride , 10mMinDMSO , 316-42-7

Synonym(s):
6ʹ,7ʹ,10,11-Tetramethoxyemetan, 2HCl;6′,7′,10,11-Tetramethoxyemetan dihydrochloride;Emetine, Dihydrochloride - CAS 316-42-7 - Calbiochem

CAS NO.:316-42-7

Empirical Formula: C29H42Cl2N2O4

Molecular Weight: 553.56

MDL number: MFCD00135589

EINECS: 206-259-8

Update time: 2022-07-08

PRODUCT Properties

Melting point: 240-250 °C (dec., dry matter)(lit.)
alpha  D +11° (c = 1) to D +21° (c = 8)
storage temp.  2-8°C
solubility  DMSO:55.36(Max Conc. mg/mL);100.0(Max Conc. mM)
form  White solid with a faint yellow cast
Water Solubility  Soluble to 100 mM in water
Merck  14,3559
Stability: Stable. Combustible. Incompatible with strong oxidizing agents. Light and heat sensitive.

Description and Uses

Emetine, an alkaloid from ipecac, C29H40O4N2, is a white powder with a very bitter taste. The substance is soluble in alcohol and ether, slightly soluble in water. Emetine darkens upon exposure to light. The compound is derived by extraction from the root of Cephalis ipecacuanha (ipecac). It is also made synthetically. Medically, ipecac is useful as an emetic (induces vomiting) for emergency use in the treatment of drug overdosage and in certain cases of poisoning. Ipecac should not be administered to persons in an unconscious state. It should be noted that emesis is not the proper treatment in all cases of potential poisoning. It should not be induced when such substances as petroleum distillates, strong alkali, acids, or strychnine are ingested.

Safety

Symbol(GHS) 
GHS06
Signal word  Danger
Hazard statements  H300-H315-H319
Precautionary statements  P264-P270-P280-P301+P310-P302+P352-P305+P351+P338
Hazard Codes  T+
Risk Statements  28-36/37/38
Safety Statements  26-28-36/37-45
RIDADR  UN 1544 6.1/PG 1
WGK Germany  3
RTECS  JY5250000
3-8-10
HazardClass  6.1(a)
PackingGroup  I
Toxicity LD50 (calculated as base) in mice (mg/kg): 32 s.c.; 30 orally (Child)

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