Tetramethylurea , Analysis standard , 632-22-4

Synonym(s):
1,1,3,3-Tetramethylurea;TMU

CAS NO.：632-22-4

Empirical Formula: C5H12N2O

Molecular Weight: 116.16

MDL number: MFCD00008319

EINECS: 211-173-9

PRODUCT Properties

• Melting point: −1 °C(lit.)
• Boiling point: 177 °C(lit.)
• Density: 0.968 g/mL at 20 °C(lit.)
• refractive index: n20/D 1.451(lit.)
• Flash point: 150 °F
• storage temp.: Inert atmosphere,Room Temperature
• solubility: Miscible with water, petroleum ether and common solvents.
• form: Liquid
• pka: 2.0(at 25℃)
• color: Clear colorless to pale yellow
• PH: 5-8 (25℃, 1M in H2O)
• Relative polarity: 5
• Odor: faint pleasant odor
• Water Solubility: H2O: 1 M at 20 °C, miscible
• Merck: 14,9230
• BRN: 773898
• Dielectric constant: 24.460000000000001
• InChIKey: AVQQQNCBBIEMEU-UHFFFAOYSA-N
• CAS DataBase Reference: 632-22-4(CAS DataBase Reference)
• NIST Chemistry Reference: Urea, tetramethyl-(632-22-4)
• EPA Substance Registry System: Tetramethylurea (632-22-4)

Description and Uses

Tetramethylurea is used as a solvent in dyestuff industries, in condensation reaction and intermediates in surfactant. It is utilized for base catalyzed isomerization and alkylation hydrocyanation due to its low permittivity. It reacts with oxalyl chloride to prepare tetramethyl chloroformamidinium chloride, which is used for the conversion of carboxylic acids and dialkyl phosphates to anhydrides and pyrophosphates respectively.

Safety

• Symbol(GHS): GHS05,GHS07,GHS08
• Signal word: Danger
• Hazard statements: H302-H315-H318-H360D
• Precautionary statements: P202-P280-P301+P312-P302+P352-P305+P351+P338-P308+P313
• Hazard Codes: Xn,T
• Risk Statements: 22-61
• Safety Statements: 53-45
• RIDADR: NA 1993 / PGIII
• WGK Germany: 3
• RTECS: YU2625000
• F: 3-10
• TSCA: Yes
• HS Code: 29241900
• Hazardous Substances Data: 632-22-4(Hazardous Substances Data)
• Toxicity: LD50 i.v. in rats: 1.1 g/kg (Lüttringhaus, Dirksen)