Home Categories Chemical Reagents 2,2,2-Trifluoroethanol
A7717312

2,2,2-Trifluoroethanol , NMRgrade,≥99.8% , 75-89-8

Synonym(s):
2,2,2-Trifluoroethanol;TFEA;transcription factor binding to IGHM enhancer 3;Transcription factor for IgH enhancer;Trifluoroethyl alcohol

CAS NO.:75-89-8

Empirical Formula: C2H3F3O

Molecular Weight: 100.04

MDL number: MFCD00004672

EINECS: 200-913-6

Update time: 2022-07-08

PRODUCT Properties

Melting point: −44 °C(lit.)
Boiling point: 77-80 °C(lit.)
Density  1.391 g/mL at 20 °C
vapor density  3.5 (vs air)
vapor pressure  70 mm Hg ( 25 °C)
refractive index  n20/D 1.3(lit.)
Flash point: 85 °F
storage temp.  Store below +30°C.
solubility  soluble in Chloroform, Methanol
pka 12.4(at 25℃)
form  Liquid
color  Clear colorless
Specific Gravity 1.373
Odor Alcoholic odour
PH Range 5-7 (10% aq soln)
explosive limit 8.4-28.8%(V)
Water Solubility  Miscible with water, ethers, ketones, alcohols and chloroform.
λmax λ: 260 nm Amax: ≤0.03
λ: 280 nm Amax: ≤0.02
Merck  14,9682
BRN  1733203
Dielectric constant 8.5500000000000007
Stability: Stable. Flammable - note wide explosion limits. Moisture sensitive. Incompatible with strong oxidizing agents, strong acids, sodium, potassium.
InChIKey RHQDFWAXVIIEBN-UHFFFAOYSA-N
CAS DataBase Reference 75-89-8(CAS DataBase Reference)
NIST Chemistry Reference Ethanol, 2,2,2-trifluoro-(75-89-8)
EPA Substance Registry System 2,2,2-Trifluoroethanol (75-89-8)

Description and Uses

2,2,2-Trifluoroethanol (Trifluoroethyl alcohol, TFE) is used to study the conformational states of proteins and the folding refolding processes of proteins.

Safety

Symbol(GHS) 
GHS02,GHS05,GHS06,GHS08
Signal word  Danger
Hazard statements  H226-H301+H331-H318-H360F-H373
Precautionary statements  P201-P210-P280-P301+P310-P304+P340+P311-P305+P351+P338
Hazard Codes  Xn,T,F
Risk Statements  10-20/21/22-37/38-41-62-38-36/37/38
Safety Statements  26-36-39-45-36/37/39-16
RIDADR  UN 1986 3/PG 3
WGK Germany  1
RTECS  KM5250000
Autoignition Temperature ~896 °F
Hazard Note  Flammable/Toxic
TSCA  Yes
HazardClass  3
PackingGroup  III
HS Code  29055910
Toxicity LD50 orally in Rabbit: 240 mg/kg LD50 dermal Rat 1680 mg/kg

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