A7716158
LB42708 , 10mMinDMSO , 226929-39-1
| Pack Size | Price | Stock | Quantity |
| 1ml | RMB559.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Boiling point: | 769.6±60.0 °C(Predicted) |
| Density | 1.39±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | ≥22.75 mg/mL in DMSO; insoluble in H2O; ≥47.5 mg/mL in EtOH |
| pka | 5.67±0.13(Predicted) |
| form | solid |
| color | Off-white to light yellow |
Description and Uses
LB 42708 is a selective nonpeptidic Farnesyltransferase (FTase) inhibitor.LB42708 suppresses tumor growth and tumor angiogenesis in both xenograft tumor models of Ras-mutated HCT116 cells and its wild-type Caco-2 cells, indicating its potential application in the treatment of both Ras-mutated and wild type tumors.
