Guanosine , 10mMinDMSO , 118-00-3

Synonym(s):
9-(β-D-Ribofuranosyl)guanine;Guanine-9-β-D-ribofuranoside

CAS NO.：118-00-3

Empirical Formula: C10H13N5O5

Molecular Weight: 283.24

MDL number: MFCD00010182

EINECS: 204-227-8

PRODUCT Properties

• Melting point: 250 °C (dec.) (lit.)
• alpha: -62 º (c=3, in 0.1 N NaOH)
• Boiling point: 425.8°C (rough estimate)
• Density: 1.3790 (rough estimate)
• refractive index: -76 ° (C=1, 1mol/L NaOH)
• storage temp.: room temp
• solubility: 0.1 M NaOH: 0.1 g/mL, clear, slightly yellow
• pka: pK1:1.9(＋1);pK2:9.25(0);pK3:12.33(OH) (25°C)
• form: Powder
• color: White to light yellow
• Odor: Odorless
• PH: 2.14；9.03
• optical activity: [α]20/D -73±2°, c = 1.5% in 1 M NaOH
• Water Solubility: 0.75 g/L (25 ºC)
• λmax: 256 (pH 0.7)；253，276 (pH 7)；256～266 (pH 11.3)
• Merck: 14,4566
• BRN: 625911
• InChIKey: NYHBQMYGNKIUIF-UUOKFMHZSA-N
• LogP: -2.331 (est)

Description and Uses

Guanosine is a purine nucleoside that is comprised of the purine base guanine attached to a ribose moiety. Mono-, di-, tri-, and cyclic monophosphorylated forms of guanosine (GMP, GDP, GTP, and cGMP, respectively) are essential for a variety of endogenous biochemical processes, such as signal transduction, metabolism, and RNA synthesis.

Guanosine has been used:

• as a reference standard for the analysis of glucosinolates by high-performance liquid chromatography with diode-array detection and electrospray ionization tandem mass spectrometry (HPLC-DAD-ESI/MS)
• as a component of Mouse Embryonic Fibroblasts (MEFs) culture
• as a standard for the detection of residual RNA contaminant in oil palm plant genome samples by HPLC

Safety

• Symbol(GHS): GHS06
• Signal word: Danger
• Hazard statements: H301
• Precautionary statements: P301+P310
• Hazard Codes: T,Xi
• Risk Statements: 25
• Safety Statements: 45-24/25-23
• RIDADR: UN 2811 6.1/PG 3
• WGK Germany: 3
• RTECS: MF8750000
• F: 10-23
• Hazard Note: Irritant
• TSCA: Yes
• HazardClass: 6.1
• PackingGroup: Ⅲ
• HS Code: 29349990