Isonicotinicacid , 10mMinDMSO , 55-22-1
Synonym(s):
INA;4-Pyridinecarboxylic acid;Pyridine-4-carboxylic acid;4-Picolinic acid;66 kDa neurofilament protein
CAS NO.：55-22-1
Empirical Formula: C6H5NO2
Molecular Weight: 123.11
MDL number: MFCD00006429
EINECS: 200-228-2
| Pack Size | Price | Stock | Quantity |
| 1ml | RMB159.20 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | ≥300 °C (lit.) |
| Boiling point: | 260 °C (15 mmHg) |
| Density | 1,47g/cm |
| refractive index | 1.5423 (estimate) |
| Flash point: | 260°C/15mm |
| storage temp. | no restrictions. |
| solubility | 6g/l |
| pka | 4.96(at 25℃) |
| form | powder |
| color | yellow to tan |
| PH | 3-4 (6g/l, H2O, 20℃)(saturated solution) |
| Water Solubility | 5.2 g/L (20 ºC) |
| Merck | 14,5187 |
| BRN | 109599 |
| InChIKey | TWBYWOBDOCUKOW-UHFFFAOYSA-N |
| CAS DataBase Reference | 55-22-1(CAS DataBase Reference) |
| NIST Chemistry Reference | Isonicotinic acid(55-22-1) |
| EPA Substance Registry System | Isonicotinic acid (55-22-1) |
Description and Uses
Isonicotinic acid is a metabolite of isoniazid. It is an isomer of nicotinic acid. The chronic toxicity of isonicotinic acid is slightly higher than that of isonicotinic acid hydrazide ( INH ) .
Isonicotinic acid is a moderately basic compound (based on its pKa). Isonicotinic acid is an organic compound with a carboxyl group on a pyridine ring. The carboxyl group for isonicotinic acid is on the 4-position instead of the 3-position for nicotinic acid. It is an isomer of nicotinic acid. Isonicotinic acid is a metabolite of isoniazid.
Isonicotinic acid considered to be inactive isomer of nicotinic acid. Isonicotinic acid is a metabolite of pyridine-4-carboxy hydrazide (isonicotinyl hydrazide; isoniazid) a front-line weapon in the battle against tuberculosis. Isonicotinic acid and its derivatives are used in manufacturing pharmaceuticals and agrochemicals.
Used in the biological study of differentiation induced by nicotinic acid, nicotinamide and isonicotinic acid in human leukemia cell lines
