Methylnicotinate , 10mMinDMSO , 93-60-7
Synonym(s):
Methyl nicotinate;Nicotinic acid methyl ester
CAS NO.：93-60-7
Empirical Formula: C7H7NO2
Molecular Weight: 137.14
MDL number: MFCD00006388
EINECS: 202-261-8
| Pack Size | Price | Stock | Quantity |
| 1ml | RMB159.20 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 42-44 °C (lit.) |
| Boiling point: | 204 °C (lit.) |
| Density | 1.2528 (rough estimate) |
| vapor pressure | 0.4 hPa (25 °C) |
| refractive index | 1.5323 (estimate) |
| FEMA | 3709 | METHYL NICOTINATE |
| Flash point: | 204 °F |
| storage temp. | Store below +30°C. |
| solubility | H2O: 0.1 g/mL, clear |
| pka | pKa 3.1 (Uncertain) |
| form | Crystals or Crystalline Powder |
| color | White to brownish |
| Odor | at 10.00 % in dipropylene glycol. warm herbal tobacco |
| Odor Type | herbal |
| Water Solubility | NEGLIGIBLE |
| Merck | 14,6100 |
| JECFA Number | 1320 |
| BRN | 113951 |
| InChIKey | YNBADRVTZLEFNH-UHFFFAOYSA-N |
| LogP | 0.68 at 25℃ |
| CAS DataBase Reference | 93-60-7(CAS DataBase Reference) |
| NIST Chemistry Reference | Methyl nicotinate(93-60-7) |
| EPA Substance Registry System | Methyl nicotinate (93-60-7) |
Description and Uses
Methyl nicotinate is a skin irritant in man, in particular producing vasodilatation, which is used on purpose in “rubefacient”, to produce a redness or inflammation for a short period of time, often in lip plumper or other lip products. Methyl nicotinate is also an active ingredient of a number of veterinary preparations intended for topical application as a rubefacient for the treatment of a variety of diseases, such as respiratory diseases, vascular disorders (oedema, haematoma), and rheumatoid disorders in cattle and horses (doses not stated; the concentration in the formulated veterinary medicinal product is 2%).
Methyl nicotinate (MN) is the methyl ester of nicotinic acid that is used as an active ingredient, a rubefacient and counter-irritant in over-the-counter topical preparations indicated for the temporary relief of aches and pains in muscles,tendons, and joints. The action of methyl nicotinate as a rubefacient is thought to involve peripheral vasodilation.For veterinary purposes，methyl nicotinate is used to treat respiratory diseases, vascular disorders, rheumatoid arthritis, and muscle and joint pains.Methyl nicotinate can be found in in guava fruit, papaya, strawberry, soursop(Annona muricata), beer, grape brandy, coffee, roasted filbert, roasted peanut and Bourbon vanilla.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38-36/38 |
| Safety Statements | 26-36-37/39 |
| WGK Germany | 3 |
| RTECS | QT1925000 |
| TSCA | Yes |
| HS Code | 29333999 |
| Toxicity | LD50 orally in Rabbit: > 2000 mg/kg |
