A7690158
Milbemycinoxime , 10mMinDMSO , 129496-10-2
CAS NO.：129496-10-2
Empirical Formula: 2C32H45NO7.2C31H43NO7
Molecular Weight: 2194.78
MDL number: MFCD09038910
EINECS: 206-141-6
| Pack Size | Price | Stock | Quantity |
| 1ml | RMB159.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 169.6-177.4° |
| Flash point: | 412℃ |
| storage temp. | Store at -20°C |
| solubility | DMSO:100.0(Max Conc. mg/mL);91.13(Max Conc. mM) |
| form | A crystalline solid |
| color | White to off-white |
| Stability: | Hygroscopic |
| InChIKey | LKMMLHTWKLEARD-MGZQXKBQSA-N |
Description and Uses
Milbemycin oxime is a semi-synthetic macrocyclic lactone prepared by the oxidation and oximation of a mixture of two natural products, milbemycin A3 and A4 (in ~30:70 ratio). Milbemycin oxime is used therapeutically for the prevention of intestinal parasites in dogs. Like the other milbemycin/avermectins, it was developed for intestinal parasite control in animals and acts by opening glutamate sensitive chloride channels in neurons of invertebrates leading to paralysis by hyperpolarisation of these cells and signal transfer blocking.
Safety
| Symbol(GHS) |  GHS09 |
| Signal word | Warning |
| Hazard statements | H410 |
| Precautionary statements | P273-P391-P501 |
| RIDADR | 2588 |
| WGK Germany | 3 |
| HazardClass | 6.1(b) |
| PackingGroup | III |
| HS Code | 2932206000 |
| Toxicity | LD50 orally in mice: 1000-1500 mg/kg (Ciba-Geigy) |
