Oxalaceticacid , 10mMinDMSO , 328-42-7
Synonym(s):
2-Oxosuccinic acid;Ketosuccinic acid;OAA;Oxalacetic acid;Oxobutanedioic acid
CAS NO.：328-42-7
Empirical Formula: C4H4O5
Molecular Weight: 132.07
MDL number: MFCD00002592
EINECS: 206-329-8
| Pack Size | Price | Stock | Quantity |
| 1ml | RMB399.20 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 161 °C (dec.)(lit.) |
| Boiling point: | 163.94°C (rough estimate) |
| Density | 1.3067 (rough estimate) |
| vapor pressure | 0.003Pa at 20℃ |
| refractive index | 1.4000 (estimate) |
| Flash point: | 88°C |
| storage temp. | -20°C |
| solubility | H2O: 100 mg/mL |
| pka | 2.22(at 25℃) |
| form | powder |
| color | White to off-white |
| PH | 3.05(1 mM solution);2.29(10 mM solution);1.68(100 mM solution) |
| Water Solubility | soluble |
| Merck | 14,6909 |
| BRN | 1705475 |
| Stability: | Stable. Incompatible with strong oxidizing agents. Keep refrigerated. |
| LogP | -1.04 at 20℃ |
| CAS DataBase Reference | 328-42-7(CAS DataBase Reference) |
| NIST Chemistry Reference | Oxalacetic acid(328-42-7) |
| EPA Substance Registry System | Oxalacetic acetic (328-42-7) |
Description and Uses
Oxaloacetic acid is an α-keto acid and a key component of cellular metabolism in its conjugate base form, oxaloacetate. Oxaloacetate reacts with acetyl-coenzyme A (acetyl-CoA; ) and water to form citrate in the first step of the citric acid cycle and is regenerated by oxidation of L-malate in the final step. It is an intermediate in gluconeogenesis that is formed in mitochondria via carboxylation of pyruvate and subsequently decarboxylated and phosphorylated to form phosphoenolpyruvate. It can be converted to aspartate via addition of an amino group from glutamate. Oxaloacetate (30 μmol/min per 100 g for 30 minutes, i.v.) reduces blood glutamate levels, severity of neurological dysfunction, and brain edema in a rat model of closed head injury.
Use as a TCA (Krebs cycle) intermediate supplement in hybridoma cell culture applications. Enhances hybridoma growth and productivity.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H319 |
| Precautionary statements | P264-P280-P305+P351+P338-P337+P313 |
| Hazard Codes | C |
| Risk Statements | 34 |
| Safety Statements | 26-36/37/39-45 |
| RIDADR | UN 3261 8/PG 2 |
| WGK Germany | 3 |
| TSCA | Yes |
| HazardClass | 8 |
| PackingGroup | II |
| HS Code | 29183000 |
