Home Categories Chemical Reagents Tris(hydroxymethyl)aminomethane hydrochloride
A7678312

Tris(hydroxymethyl)aminomethane hydrochloride , Super pure level, ≥99% , 1185-53-1

Synonym(s):
TRIS HCl;TRIS hydrochloride;Trizma hydrochloride;Tris(hydroxymethyl)aminomethane hydrochloride;tris(Hydroxymethyl)aminomethane, HCl

CAS NO.:1185-53-1

Empirical Formula: C4H12ClNO3

Molecular Weight: 157.6

MDL number: MFCD00012590

EINECS: 214-684-5

Pack Size Price Stock Quantity
25G RMB39.20 In Stock
100G RMB84.80 In Stock
500G RMB388.80 In Stock
2.5kg RMB1613.60 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 150-152 °C
Boiling point: 225℃[at 101 325 Pa]
Density  1.05 g/mL at 20 °C
vapor pressure  0Pa at 20℃
storage temp.  room temp
solubility  H2O: 4 M at 20 °C, clear, colorless
form  crystalline
color  clear colorless (40 % (w/w) in H2O) solution
PH Range 7.0 - 9.0
PH 2.5-4.0 (25℃, 4M in H2O)
pka 8.1(at 25℃)
Water Solubility  SOLUBLE
Sensitive  Hygroscopic
λmax λ: 260 nm Amax: 0.12
λ: 280 nm Amax: 0.08
BRN  3675235
Stability: Stable. Incompatible with strong oxidizing agents, bases, moisture.
InChIKey QKNYBSVHEMOAJP-UHFFFAOYSA-N
LogP -3.6 at 20℃
CAS DataBase Reference 1185-53-1(CAS DataBase Reference)
EPA Substance Registry System 1,3-Propanediol, 2-amino-2-(hydroxymethyl)-, hydrochloride (1185-53-1)

Description and Uses

Abbreviated as Tris HCl (TRIS hydrochloride), Tris (hydroxymethyl) aminomethane hydrochloride is an organic compound commonly utilized in buffer solutions such as TAE or TBE for electrophoresis gels. It boasts high solubility in water and offers utility within the pH range of 7.0-9.0.

Tris Hydrochloride is a buffering medium for electrophoresis, molecular biology, and cell culture applications. It may be combined with Tris Base to simplify Tris buffer preparation. Tris Hydrochloride has been incorporated in coelomic fluid and in Cortland medium to store unfertilized rainbow trout eggs. In immunohistochemistry, Tris Hydrochloride has also been used with urea as a method for antigen retrieval.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
RTECS  TY2900000
3
TSCA  Yes
HS Code  29221980

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