Indinavirsulfate , 10mMinDMSO , 157810-81-6
CAS NO.：157810-81-6
Empirical Formula: C36H49N5O8S
Molecular Weight: 711.87
MDL number: MFCD00920346
EINECS: 682-418-9
| Pack Size | Price | Stock | Quantity |
| 1ml | RMB159.20 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 150-153°C (dec) |
| storage temp. | -20°C Freezer |
| solubility | Freely soluble in water, soluble in methanol, practically insoluble in heptane. |
| form | Solid |
| color | White to Off-White |
| Water Solubility | >100g/L(temperature not stated) |
| BCS Class | 2,4 |
Description and Uses
Indinavir is an HIV-1 protease inhibitor (Ki = 0.358 nM). It is selective for HIV-1 protease over HIV-2 protease (Ki = 3.316 nM), as well as human cathepsin D, porcine pepsin, bovine chymosin, human plasma renin, Factor Xa, and elastase at 10 μM. It is also selective for wild-type HIV-1 protease over the protease inhibitor-resistant mutants A-44, K-60, and V-18 (Kis = 0.24, 15, 50, and 40 nM, respectively). Indinavir is active against multiple HIV-1 variants in cell-based assays (IC95s = 12-100 nM). Formulations containing indinavir have been used in combination with antiretroviral agents in the treatment of HIV infection.
Indinavir Sulfate is a member of the novel hydroxyaminopentane amide class of HIV-1 protease inhibitors. Antiviral. It is a COVID19-related research product.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
