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A7675358

Indinavirsulfate , 10mMinDMSO , 157810-81-6

CAS NO.:157810-81-6

Empirical Formula: C36H49N5O8S

Molecular Weight: 711.87

MDL number: MFCD00920346

EINECS: 682-418-9

Pack Size Price Stock Quantity
1ml RMB159.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 150-153°C (dec)
storage temp.  -20°C Freezer
solubility  Freely soluble in water, soluble in methanol, practically insoluble in heptane.
form  Solid
color  White to Off-White
Water Solubility  >100g/L(temperature not stated)
BCS Class 2,4

Description and Uses

Indinavir is an HIV-1 protease inhibitor (Ki = 0.358 nM). It is selective for HIV-1 protease over HIV-2 protease (Ki = 3.316 nM), as well as human cathepsin D, porcine pepsin, bovine chymosin, human plasma renin, Factor Xa, and elastase at 10 μM. It is also selective for wild-type HIV-1 protease over the protease inhibitor-resistant mutants A-44, K-60, and V-18 (Kis = 0.24, 15, 50, and 40 nM, respectively). Indinavir is active against multiple HIV-1 variants in cell-based assays (IC95s = 12-100 nM). Formulations containing indinavir have been used in combination with antiretroviral agents in the treatment of HIV infection.

Indinavir Sulfate is a member of the novel hydroxyaminopentane amide class of HIV-1 protease inhibitors. Antiviral. It is a COVID19-related research product.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338
Hazardous Substances Data 157810-81-6(Hazardous Substances Data)

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