A7656412
Triphosgene , 99% , 32315-10-9
Synonym(s):
Bis(trichloromethyl) carbonate;Triphosgene;tri-Phosgene;Triphosgene, Carbonic acid bistrichlor methyl ester
CAS NO.：32315-10-9
Empirical Formula: C3Cl6O3
Molecular Weight: 296.73
MDL number: MFCD00062848
EINECS: 250-986-3
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 79-83 °C (lit.) |
| Boiling point: | 203-206 °C (lit.) |
| Density | 1.78 |
| vapor pressure | 16 hPa (90 °C) |
| Flash point: | 203-206°C |
| storage temp. | 2-8°C |
| solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. |
| form | Crystalline Powder, Crystals and/or Chunks |
| color | White to off-white |
| Water Solubility | practically insoluble |
| Sensitive | Moisture Sensitive |
| BRN | 1787583 |
| InChIKey | UCPYLLCMEDAXFR-UHFFFAOYSA-N |
| CAS DataBase Reference | 32315-10-9(CAS DataBase Reference) |
| EPA Substance Registry System | Methanol, trichloro-, carbonate (2:1) (32315-10-9) |
Description and Uses
Triphosgene is also known as solid phosgene. Its chemical name is bis (Trichloromethyl) carbonate, and its English name is bisgriehloromethyl) carbonate or triphosgene, abbreviated as BTC. Triphosgene is a white crystal, similar to the smell of phosgene. It is mainly used to synthesize chloroformate, isocyanate, polycarbonate and acyl chloride. It is widely used as an intermediate in plastics, medicine, herbicides and pesticides.
Triphosgene can be employed as a reagent to prepare:
- Thiocarbonates from thiols and alcohols by one-pot, three-component reaction.
- Substituted azetidin-2-ones from acids and imines via ketene–imine cycloaddition reaction.
- Methyl (S)-2-isocyanato-3-phenylpropanoate from L-phenylalanine methyl ester hydrochloride in the presence of sodium bicarbonate.
- Acyl azides derivatives from various carboxylic acids and sodium azide.
- Immunosuppressant agent cyclosporin by solid-phase peptide synthesis.
- Allyl azides from allyl alcohols and sodium azide in one pot method.
- Esterification coupling reagent di-2-thienyl carbonate, from 2(5H)-thiophenone.
- 2-Chloronicotinaldehydes via cyclization of the corresponding enamides.
Safety
| Symbol(GHS) |   GHS05,GHS06 |
| Signal word | Danger |
| Hazard statements | H314-H330 |
| Precautionary statements | P260-P271-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338 |
| Hazard Codes | T+,Xn,T |
| Risk Statements | 26-34-29-36/37/38-20/21/22-23/24/25 |
| Safety Statements | 36/37/39-45-9-26-36-7/9 |
| RIDADR | UN 2928 6.1/PG 2 |
| WGK Germany | 2 |
| F | 10-19-21 |
| TSCA | Yes |
| HazardClass | 6.1 |
| PackingGroup | II |
| HS Code | 29209010 |
