3,4,5-Trifluorophenylboronic acid , 97% , 143418-49-9

Synonym(s):
3,4,5-Trifluorobenzeneboronic acid

CAS NO.：143418-49-9

Empirical Formula: C6H4BF3O2

Molecular Weight: 175.9

MDL number: MFCD02093069

EINECS: 604-355-8

PRODUCT Properties

• Melting point: 290-295 °C (lit.)
• Boiling point: 263.6±50.0 °C(Predicted)
• Density: 1,087g/cm
• refractive index: 1,423-1,425
• storage temp.: Keep in dark place,Sealed in dry,Room Temperature
• solubility: 18.43g/l
• pka: 6.54±0.11(Predicted)
• form: Powder
• color: Tan
• BRN: 7371914
• InChI: InChI=1S/C6H4BF3O2/c8-4-1-3(7(11)12)2-5(9)6(4)10/h1-2,11-12H
• InChIKey: UHDDEIOYXFXNNJ-UHFFFAOYSA-N
• SMILES: B(C1=CC(F)=C(F)C(F)=C1)(O)O

Description and Uses

3,4,5-Trifluorophenylboronic acid is an arylboronic acid compound used in organic synthesis and as a reaction reagent. It can be used as a catalyst to catalyse the direct amidation of amino acid derivatives and the direct polycondensation of carboxylic acids and amines; it can also be used in the formation of new 1:1 co-crystals with urea C6H4BF3O2-CH4N2O components.

Reactant involved in:

• Preparation of phenylboronic catechol esters and determination of Lewis acidity
• Synthesis of benzopyranone derivatives as GABAA receptor modulators
• Synthesis of multisubstituted olefins and conjugate dienes
• Suzuki cross-coupling reactions
• Preparation of fluorinated aromatic poly(ether-amide)s

Safety

• Symbol(GHS): GHS07,GHS09
• Signal word: Warning
• Hazard statements: H302-H319-H411
• Precautionary statements: P273-P301+P312+P330-P305+P351+P338
• Hazard Codes: N-Xn,Xi
• Risk Statements: 51/53-36-22-36/37/38
• Safety Statements: 61-26-37/39-36
• RIDADR: 3077
• WGK Germany: 3
• HazardClass: IRRITANT
• HS Code: 29163990