Misoprostol , 10mMinDMSO , 59122-46-2
Synonym(s):
(±)-15-Deoxy-(16RS)-16-hydroxy-16-methylprostaglandin E1;(±)-15-Deoxy-(16RS)-16-hydroxy-16-methylprostaglandin E1 methyl ester
CAS NO.：59122-46-2
Empirical Formula: C22H38O5
Molecular Weight: 382.54
MDL number: MFCD07772001
EINECS: 664-288-5
| Pack Size | Price | Stock | Quantity |
| 1ml | RMB559.20 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 261-263°C |
| Boiling point: | 429.67°C (rough estimate) |
| Density | 1.0323 (rough estimate) |
| refractive index | 1.6120 (estimate) |
| storage temp. | Sealed in dry,Store in freezer, under -20°C |
| solubility | Practically insoluble in water, soluble in ethanol (96 per cent), sparingly soluble in acetonitrile. |
| pka | 13.92±0.60(Predicted) |
Description and Uses
Misoprostol is an orally-active PGEl analog useful in the treatment of gastric and duodenal ulcers. As with other agents of this type, misoprostol may prove useful as a gastric cytoprotective when administered concurrently with irritating drugs such as nonsteroidal antiinflammatories.
Misoprostol is a cytoprotective prostaglandin PGE1 analogue that inhibits gastric acid secretion. It has many medical uses, including nine obstetric indications. The drug was originally produced by Pfizer for the treatment of gastric ulcers. Misoprostol is commonly used to prevent NSAID-induced gastric ulcers in patients at high risk of complications from a gastric ulcer, such as elderly patients and patients with a history of ulcer. It has also been used in treating duodenal ulcers unresponsive to histamine H2-antagonists; the drug does not prevent duodenal ulcers,however, in patients taking NSAIDS. Misoprostol can cause miscarriage, often associated with potentially dangerous bleeding.
Safety
| Symbol(GHS) |   GHS06,GHS08 |
| Signal word | Danger |
| Hazard statements | H301-H360 |
| Precautionary statements | P201-P280-P301+P330+P331+P310-P308+P313 |
| Hazard Codes | T |
| Risk Statements | 45-60-61-25-36/37/38 |
| Safety Statements | 53-22-36/37/39-45 |
| RIDADR | UN 2810 6.1/PG 3 |
| WGK Germany | 2 |
| RTECS | UK8390000 |
| HS Code | 2937500000 |
| Toxicity | LD50 in rats, mice (mg/kg): 40-62, 70-160 i.p.; 81-100, 27-138 orally (Kotsonis) |
