Home Categories Pharmaceutical intermediates Tetrahydropyran
A7638212

Tetrahydropyran , 99% , 142-68-7

Synonym(s):
Pentamethylene oxide

CAS NO.:142-68-7

Empirical Formula: C5H10O

Molecular Weight: 86.13

MDL number: MFCD00006585

EINECS: 205-552-8

Update time: 2022-07-08

PRODUCT Properties

Melting point: -45 °C (lit.)
Boiling point: 88 °C (lit.)
Density  0.881 g/mL at 25 °C (lit.)
vapor density  3 (vs air)
refractive index  n20/D 1.42(lit.)
Flash point: 4 °F
storage temp.  Store below +30°C.
solubility  >80.2g/l
form  Liquid
color  Clear colorless
Odor at 0.10?%?in?dipropylene glycol. pungent sweet ethereal
Water Solubility  80 g/L (25 ºC)
Merck  14,9217
BRN  102436
Dielectric constant 7.3(30℃)
InChIKey DHXVGJBLRPWPCS-UHFFFAOYSA-N
LogP 0.950

Description and Uses

Tetrahydropyran (THP) is the organic compound consisting of a saturated six-membered ring containing five carbon atoms and one oxygen atom. It is named by reference to pyran, which contains two double bonds, and may be produced from it by adding four hydrogens. Tetrahydropyran can be used as a solvent in various classical organic reactions such as radical reactions, palladium-catalyzed coupling, and Grignard reactions.

It is is an important raw material and intermediate used in Organic Synthesis, Pharmaceuticals, Agrochemicals and dyestuff. They are also used as important solvents, as chemical intermediate and as monomer for ring-opening polymerization.

Safety

Symbol(GHS) 
GHS02
Signal word  Danger
Hazard statements  H225
Precautionary statements  P210-P233-P240-P241-P242-P243
Hazard Codes  F,Xi,Xn
Risk Statements  11-36/37/38-9-19-52/53-22
Safety Statements  9-16-26-33-36-61
RIDADR  UN 1993 3/PG 2
WGK Germany  3
TSCA  Yes
HazardClass  3
PackingGroup  II
HS Code  29321100

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