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A7625358

Hydrocortisone21-acetate , 10mMinDMSO , 50-03-3

Synonym(s):
11β,17α,21-Trihydroxy-4-pregnene-3,20-dione 21-acetate;17-α-Hydroxycorticosterone acetate;17-Hydroxycorticosterone 21-acetate;21-Acetoxy-4-pregnene-11β,17α-diol-3,20-dione;4-Pregnene-11β,17α,21-triol-3,20-dione 21-acetate

CAS NO.:50-03-3

Empirical Formula: C23H32O6

Molecular Weight: 404.5

MDL number: MFCD00037714

EINECS: 200-004-4

Pack Size Price Stock Quantity
1ml RMB159.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 223 °C (dec.)(lit.)
Boiling point: 446.1°C (rough estimate)
alpha  D25 +166° (c = 0.4 in dioxane); D25 +150.7° (c = 0.5 in acetone)
Density  d420 1.289
refractive index  1.4593 (estimate)
Flash point: 223°C
storage temp.  0-6°C
solubility  Practically insoluble in water, slightly soluble in anhydrous ethanol and in methylene chloride
pka 12.42±0.70(Predicted)
form  Solid
color  White to Off-White
Water Solubility  Insoluble in water.
Decomposition  223 ºC
Merck  14,4787
BRN  2066841
Stability: Stable, but may be light or moisture sensitive. Incompatible with strong oxidizing agents.
LogP 2.190
CAS DataBase Reference 50-03-3(CAS DataBase Reference)
NIST Chemistry Reference Hydrocortisone acetate(50-03-3)

Description and Uses

Hydrocortisone acetate is used to treat hemorrhoids and itching/swelling in the rectum and anus. It is used to treat certain intestinal problems (such as ulcerative colitis of the rectum and other rectal/anal inflammatory conditions).

Safety

Symbol(GHS) 
GHS08
Signal word  Danger
Hazard statements  H360Df-H373
Precautionary statements  P202-P260-P280-P308+P313-P405-P501
Hazard Codes  Xn,T
Risk Statements  63-10-45
Safety Statements  36/37-45-53
WGK Germany  3
RTECS  GM8960000
HS Code  29372100
Toxicity LD50 intraperitoneal in mouse: 2300mg/kg

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