A7622058
ItoprideHydrochloride , 10mMinDMSO , 122892-31-3
Synonym(s):
N-[[4-[2-(Dimethylamino)ethoxy]phenyl]methyl]-3,4-dimethoxy benzamidehydrochloride;N-[p-[2-(dimethylamino)ethoxy]benzyl]veratramide hydrochloride
CAS NO.:122892-31-3
Empirical Formula: C20H27ClN2O4
Molecular Weight: 394.89
MDL number: MFCD00881710
EINECS: 602-905-1
Pack Size | Price | Stock | Quantity |
1ml | RMB239.20 | In Stock |
|
others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
Melting point: | 194-1950C |
storage temp. | 2-8°C |
solubility | H2O: ≥48mg/mL |
form | powder |
color | white to tan |
λmax | 258nm(MeOH)(lit.) |
Merck | 14,5244 |
CAS DataBase Reference | 122892-31-3(CAS DataBase Reference) |
Description and Uses
Itopride, a gastroprokinetic benzamide derivative was launched in Japan for the relief of gastrointestinal symptoms in patients with chronic gastritis. ltopride is a dopamine D2-receptor antagonist that stimulates acetylcholine (Ach) release on the postganglionic cholinergic neurons to cause Ach accumulation at muscarinic receptors and, therefore, enhances Ach-induced gastric contractions. In animal models, itopride was reported to increase GI transit and gastric emptying.
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