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A7622058

ItoprideHydrochloride , 10mMinDMSO , 122892-31-3

Synonym(s):
N-[[4-[2-(Dimethylamino)ethoxy]phenyl]methyl]-3,4-dimethoxy benzamidehydrochloride;N-[p-[2-(dimethylamino)ethoxy]benzyl]veratramide hydrochloride

CAS NO.:122892-31-3

Empirical Formula: C20H27ClN2O4

Molecular Weight: 394.89

MDL number: MFCD00881710

EINECS: 602-905-1

Pack Size Price Stock Quantity
1ml RMB239.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 194-1950C
storage temp.  2-8°C
solubility  H2O: ≥48mg/mL
form  powder
color  white to tan
λmax 258nm(MeOH)(lit.)
Merck  14,5244
CAS DataBase Reference 122892-31-3(CAS DataBase Reference)

Description and Uses

Itopride, a gastroprokinetic benzamide derivative was launched in Japan for the relief of gastrointestinal symptoms in patients with chronic gastritis. ltopride is a dopamine D2-receptor antagonist that stimulates acetylcholine (Ach) release on the postganglionic cholinergic neurons to cause Ach accumulation at muscarinic receptors and, therefore, enhances Ach-induced gastric contractions. In animal models, itopride was reported to increase GI transit and gastric emptying.

Anti-Spasmodics

Safety

Symbol(GHS) 
GHS09
Signal word  Warning
Hazard statements  H410
Precautionary statements  P273-P501
Hazard Codes  N
Risk Statements  50
Safety Statements  61
RIDADR  UN 3077 9 / PGIII
WGK Germany  3
RTECS  CV4552000
HS Code  2924.29.7790

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