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A7612858

γ-Oryzanol , 10mMinDMSO , 11042-64-1

CAS NO.:11042-64-1

Empirical Formula: C40H58O4

Molecular Weight: 602.89

MDL number: MFCD00867548

EINECS: 600-960-6

Pack Size Price Stock Quantity
1ml RMB159.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 135-137°C
Boiling point: 571.92°C (rough estimate)
Density  0.9751 (rough estimate)
refractive index  1.4760 (estimate)
storage temp.  Sealed in dry,Room Temperature
Water Solubility  Practically insoluble in water
solubility  Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form  powder to crystaline
color  White to Light yellow
Odor little or no odor
Merck  14,6886
LogP 13.205 (est)

Description and Uses

Gamma oryzanol is a lipid fraction derived from rice-bran oil. Oryzanol was first isolated from rice-bran oil in the 1950s. Several lipid fractions were isolated from the oil.The third (gamma) fraction isolated was oryzanol.It is made up of a mixture of ferulic acid esters and plant sterols. Similar in structure to cholesterol, the phytosterols and triterpenes that comprise oryzanol include campesterol, stigmasterol, beta sitosterol, cycloartanol, and cycloartenol. Because phytosterols are poorly absorbed, it has been suggested that they may reduce blood cholesterol by inhibiting intestinal cholesterol absorption.In contrast, the ferulic acid portion of gamma oryzanol is easily absorbed into the body's tissues. Ferulic acid also has demonstrated antioxidant properties in vitro.

Gamma Oryzanol is a mixture of 6 substances derived from rice bran oil, including sterols and ferulic acid, called Cycloartanyl Ferulate or Triterpene alcohol ferulate. It has been approved in Japan for several conditions, including menopausal symptoms, mild anxiety, stomach upset, and high cholesterol. In the US, it is widely used as a sports supplement, as well as for reducing cholesterol. gamma oryzanol is widely used as a food additive, pharmaceutical material. In cosmetic area, the application to creams and sunscreens exploiting its skin age resistor function and ultraviolet absorbing effect.

Safety

Symbol(GHS) 
GHS06
Signal word  Danger
Hazard statements  H310
Precautionary statements  P501-P270-P262-P264-P280-P361+P364-P302+P352+P310-P405
RIDADR  UN 2811 6.1/PG II
RTECS  RN0050000
HS Code  3822.19.0080
HazardClass  6.1
PackingGroup  II
Toxicity LD50 oral in rat: > 25gm/kg

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