Home Categories Analytical Chemistry MefloquineHydrochloride
A7607258

MefloquineHydrochloride , 10mMinDMSO , 51773-92-3

Synonym(s):
(AS)-rel-a-(2R)-2-Piperidinyl-2,8-bis(trifluoromethyl)-4-quinolinemethanol monohydrochloride;Mefloquine hydrochloride;MQ

CAS NO.:51773-92-3

Empirical Formula: C17H17ClF6N2O

Molecular Weight: 414.77

MDL number: MFCD00797519

EINECS: 257-412-0

Pack Size Price Stock Quantity
1ml RMB159.20 In Stock
others     Enquire
Update time: 2022-07-08

PRODUCT Properties

Melting point: 250-254?C
storage temp.  2-8°C
solubility  DMSO: 38 mg/mL, soluble
form  solid
color  white
λmax 222nm(Acidic H2O)(lit.)
Merck  14,5801
BCS Class 4/2
Stability: Temperature Sensitive
InChI InChI=1/C17H16F6N2O.ClH/c18-16(19,20)11-5-3-4-9-10(15(26)12-6-1-2-7-24-12)8-13(17(21,22)23)25-14(9)11;/h3-5,8,12,15,24,26H,1-2,6-7H2;1H/t12-,15+;/s3
InChIKey WESWYMRNZNDGBX-YLCXCWDSSA-N
SMILES C12N=C(C=C([C@@H](O)[C@@]3([H])NCCCC3)C=1C=CC=C2C(F)(F)F)C(F)(F)F.Cl |&1:5,7,r|

Description and Uses

Mefloquine hydrochloride is an erythrocytic schizonticide useful, in combination with sulfadoxine and pyrimethamine, in the prophylaxis and treatment of malaria. Administered once weekly, the combination is effective against pathogens resistant to other agents.

Antimalarial;Heme polymerase inhibitor

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P301+P312+P330
Hazard Codes  Xn
Risk Statements  22
RIDADR  UN 3077 9 / PGIII
WGK Germany  3
RTECS  VC0308000
HS Code  2933399090

RELATED PRODUCTS