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A7605958

L-Serine , 10mMinWater , 56-45-1

Synonym(s):
L-Serine;Ser;L-Serine - CAS 56-45-1 - Calbiochem;(S)-2-Amino-3-hydroxypropionic acid;(S)-(+)-Serine

CAS NO.:56-45-1

Empirical Formula: C3H7NO3

Molecular Weight: 105.09

MDL number: MFCD00064224

EINECS: 200-274-3

Pack Size Price Stock Quantity
1ml RMB159.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 222 °C (dec.) (lit.)
Boiling point: 197.09°C (rough estimate)
alpha  15.2 º (c=10, 2N HCl)
Density  1.6
refractive index  1.4368 (estimate)
Flash point: 150°C
storage temp.  2-8°C
solubility  H2O: 50 mg/mL
form  powder
pka 2.19(at 25℃)
color  White
PH 5-6 (100g/l, H2O, 20℃)
Odor wh. cryst. or cryst. powd., odorless, sweet taste
optical activity [α]20/D +13.5±0.5°, c = 5% in 5 M HCl
Water Solubility  250 g/L (20 ºC)
λmax λ: 260 nm Amax: 0.05
λ: 280 nm Amax: 0.05
Merck  14,8460
Sublimation  150 ºC
BRN  1721404
Stability: Stable. Incompatible with strong oxidizing agents.
InChIKey MTCFGRXMJLQNBG-REOHCLBHSA-N
LogP -1.580
CAS DataBase Reference 56-45-1(CAS DataBase Reference)
NIST Chemistry Reference L-Serine(56-45-1)
EPA Substance Registry System L-Serine (56-45-1)

Description and Uses

Serine (abbreviated as Ser or S) is an amino acid with the formula HO2CCH(NH2)CH2OH. It is one of the proteinogenic amino acids. Its codons in the genetic code are UCU, UCC, UCA, UCG, AGU and AGC. By virtue of the hydroxyl group, serine is classified as a polar amino acid.
L-serine is an amino acid essential for the synthesis of phosphatidylserine, which is a component of the membrane of brain cells (i.e., neurons). It can be produced in the body, including the brain, but an external supply from the diet is essential in maintaining necessary levels. Although preclinical studies suggest L-serine may inhibit inflammation in the brain, levels of L-serine in humans do not appear to be associated with dementia or cognitive decline. Because L-serine is a naturally occurring amino acid, supplementation is likely safe in moderation.

L-Serine is classified as a non-essential amino acid. It is used as a cell culture media component and raw material for the commercial biomanufacture of therapeutic recombinant proteins and monoclonal antibodies.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P301+P312-P302+P352-P304+P340-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  24/25-36-26
WGK Germany  3
RTECS  VT8100000
3
TSCA  Yes
HS Code  29225000
Hazardous Substances Data 56-45-1(Hazardous Substances Data)

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