PRODUCT Properties
| Melting point: | 105-107 °C (lit.) |
| Boiling point: | 280-281 °C (lit.) |
| Density | 1.39 |
| refractive index | 1.5939 (estimate) |
| Flash point: | 210 °C |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | 450g/l |
| pka | 0.75(at 20℃) |
| form | Liquid |
| color | Colorless to yellow to brown, darken on storage with no loss of purity |
| Water Solubility | Soluble in water 450 g/L @ 20°C and ethanol, slightly soluble in benzene and ether. |
| BRN | 105786 |
| LogP | -0.593 (est) |
| CAS DataBase Reference | 142-08-5(CAS DataBase Reference) |
| NIST Chemistry Reference | 2(1H)-Pyridinone(142-08-5) |
| EPA Substance Registry System | 2(1H)-Pyridinone (142-08-5) |
Description and Uses
2-Hydroxypyridine is a bifunctional catalyst for a wide variety of acylation reactions, catalyst for generating β-oxopropyl carbonates from cyclic carbonates and alcohols and in the aminolysis of a polyglutamate. It is used in peptide synthesis.
Safety
| Symbol(GHS) |  GHS06 |
| Signal word | Danger |
| Hazard statements | H301 |
| Precautionary statements | P301+P330+P331+P310 |
| Hazard Codes | Xi,Xn,T |
| Risk Statements | 36/37/38-40-25 |
| Safety Statements | 26-36-37/39-22-45-36/37/39 |
| RIDADR | UN2811 |
| WGK Germany | 3 |
| RTECS | UV1144050 |
| F | 8 |
| TSCA | Yes |
| HazardClass | 6.1 |
| PackingGroup | III |
| HS Code | 29333990 |
| Toxicity | LD50 ipr-mus: 410 mg/kg TOXIA6 23,815,85 |
