Fimasartan , 10mMinDMSO , 247257-48-3

Synonym(s):
2-Butyl-1,6-dihydro-N,N,4-trimethyl-6-oxo-1-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-5-pyrimidineethanethioamide;2-n-Butyl-5-dimethylaminothiocarbonylmethyl-6-methyl-3-[[2′-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]pyrimidin-4(3H)-one;BR-A657;BR-A-657

CAS NO.：247257-48-3

Empirical Formula: C27H31N7OS

Molecular Weight: 501.65

MDL number: MFCD13194795

PRODUCT Properties

• Melting point: >155°C (dec.)
• Boiling point: 693.0±65.0 °C(Predicted)
• Density: 1.25
• storage temp.: 2-8°C
• solubility: DMSO (Slightly), Methanol (Slightly)
• form: Solid
• pka: 4.16±0.10(Predicted)
• color: White to Off-White

Description and Uses

Fimasartan is an angiotensin II receptor antagonist (ARB) drug employed in the treatment of both hypertension and heart failure. It has been found to be safe when administered with hydrochlorothiazide (a diuretic) in clinical trials. Fimasartan was initially approved September 9th, 2010 in South Korea and is marketed under the brand name Kanarb by Boryung Pharmaceuticals.

Fimasartan is a new angiotensin II receptor blocker antagonist and also functions as an antihypertensive agent.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302
• Precautionary statements: P280-P305+P351+P338