(±)-6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylicacid , 10mMinDMSO , 53188-07-1

Synonym(s):
Trolox

CAS NO.：53188-07-1

Empirical Formula: C14H18O4

Molecular Weight: 250.29

MDL number: MFCD00006846

EINECS: 258-422-8

PRODUCT Properties

• Melting point: 187-189 °C (lit.)
• Boiling point: 313.42°C (rough estimate)
• Density: 1.0616 (rough estimate)
• refractive index: 1.4970 (estimate)
• storage temp.: 2-8°C
• solubility: Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml). Also soluble in Water at alkalinepH.
• form: Crystalline Powder
• pka: 3.35±0.20(Predicted)
• color: White to faintly beige
• BRN: 1384051
• Stability: Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
• InChI: InChI=1S/C14H18O4/c1-7-8(2)12-10(9(3)11(7)15)5-6-14(4,18-12)13(16)17/h15H,5-6H2,1-4H3,(H,16,17)
• InChIKey: GLEVLJDDWXEYCO-UHFFFAOYSA-N
• SMILES: C1(C)(C(O)=O)OC2=C(C)C(C)=C(O)C(C)=C2CC1
• CAS DataBase Reference: 53188-07-1(CAS DataBase Reference)
• EPA Substance Registry System: 3,4-Dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-carboxylic acid (53188-07-1)

Description and Uses

Trolox (53188-07-1) is a water soluble derivative of vitamin E. Displays antioxidant and radical scavenging activities.1 Prevents lipid peroxidation induced by CYP2E1 in Hep G2 cells.2 Trolox inhibits peroxynitrite-mediated oxidative stress and apoptosis in rat thymocytes.3

Trolox is a Vitamin E analog that also maintains the antioxidant capabilities which Vitamin E shows. Neuroprotective product.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P305+P351+P338-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 2
• RTECS: DJ2273000
• HS Code: 29339900