IpratropiumBromideMonohydrate , 10mMinDMSO , 66985-17-9

Synonym(s):
Atropine isopropyl bromide;Ipratropium bromide monohydrate

CAS NO.：66985-17-9

Empirical Formula: C20H32BrNO4

Molecular Weight: 430.38

MDL number: MFCD04108705

EINECS: 622-130-2

PRODUCT Properties

• Melting point: 231 °C
• storage temp.: 2-8°C
• solubility: H2O: soluble10mg/mL
• form: powder
• color: white
• Stability: Hygroscopic
• InChIKey: KEWHKYJURDBRMN-XSAPEOHZNA-M
• SMILES: C([N+]1([C@@H]2C[C@@H](OC(=O)C(C3C=CC=CC=3)CO)C[C@H]1CC2)C)(C)C.[Br-].O |&1:2,4,18,r|

Description and Uses

Ipratropium bromide is a quaternary ammonium congener of atropine and is an anticholinergic compound approved for use as a bronchodilator. Anticholinergic agents produce bronchodilatation by antagonizing the activity of acetylcholine at the level of its receptor, particularly those found on airway smooth muscle in the large, central airways. The onset of action of ipratropium is relatively slow (20 minutes), and the peak effect occurs at 60 minutes.1 Ipratropium, unlike atropine, is poorly absorbed across mucous membranes and has little toxicity at the usual doses.

antihypertensive

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302+H332-H319
• Precautionary statements: P261-P264-P270-P301+P312-P304+P340+P312-P305+P351+P338
• Hazard Codes: Xn
• Risk Statements: 20/22-36
• Safety Statements: 26
• RTECS: YM3700000
• HS Code: 2939800000