PRODUCT Properties
| Melting point: | 49-51 °C(lit.) |
| Boiling point: | 165 °C10 mm Hg(lit.) |
| Density | 1.0326 (rough estimate) |
| refractive index | 1.5405 (estimate) |
| Flash point: | >230 °F |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | 5.3g/l. Almost insoluble in water, soluble in alcohol and oils |
| form | Crystalline Powder |
| pka | 4.76(at 25℃) |
| color | White to slightly yellow |
| Water Solubility | 5.3 g/L at 40 ºC |
| BRN | 638180 |
| InChIKey | OBKXEAXTFZPCHS-UHFFFAOYSA-N |
| LogP | 2.420 |
| CAS DataBase Reference | 1821-12-1(CAS DataBase Reference) |
| NIST Chemistry Reference | 4-Phenylbutanoic acid(1821-12-1) |
| EPA Substance Registry System | 4-Phenylbutyric acid (1821-12-1) |
Description and Uses
4-Phenylbutyric acid is used as a chemical chaperone involved in protein-folding disorders. It is involved in the synthesis of dyes and an active pharmaceutical ingredient intermediate.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H335-H315-H319 |
| Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P280a-P304+P340-P305+P351+P338-P405-P501a |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 22-24/25-36-26 |
| WGK Germany | 3 |
| Hazard Note | Irritant |
| TSCA | Yes |
| HS Code | 29163900 |
