A7567358
NSC87877 , 10mMinDMSO , 56932-43-5
Synonym(s):
8-Hydroxy-7-(6-sulfonaphthalen-2-yl)diazenyl-quinoline-5-sulfonic acid, Disodium Salt, HePTP Inhibitor II, PTP Inhibitor XXV, PTP1B Inhibitor IV, SHP1 Inhibitor I, SHP2 Inhibitor I;SHP1/2 PTPase Inhibitor, NSC-87877 - CAS 56932-43-5 - Calbiochem
CAS NO.：56932-43-5
Empirical Formula: C19H11N3Na2O7S2
Molecular Weight: 503.42
MDL number: MFCD00041863
EINECS: 260-449-5
| Pack Size | Price | Stock | Quantity |
| 1ml | RMB712.80 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| storage temp. | Inert atmosphere,Room Temperature |
| form | Solid |
| color | Brown to black |
| Water Solubility | water: 10mg/mL |
| EPA Substance Registry System | 5-Quinolinesulfonic acid, 8-hydroxy-7-[(6-sulfo-2-naphthalenyl)azo]-, disodium salt (56932-43-5) |
Description and Uses
NSC-87877 disodium is a potent inhibitor of Shp2 and Shp1 protein tyrosine phosphatases (SH-PTP2 and SH-PTP1), with IC50 values of 0.318 μM, 0.355 μM shp2 and shp1, respectively[1]. NSC-87877 also inhibits dual-specificity phosphatase 26 (DUSP26)[2].
Safety
| Safety Statements | 24/25 |
