Home Categories Biochemical Engineering <small>L</small>-Kynurenine Hydrate
A7399412

<small>L</small>-Kynurenine Hydrate , >98.0%(T) , 2922-83-0

Synonym(s):
β-Anthraniloyl-L-alanine;L-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid

CAS NO.:2922-83-0

Empirical Formula: C10H12N2O3

Molecular Weight: 208.21

MDL number: MFCD00069912

Pack Size Price Stock Quantity
25MG RMB127.20 In Stock
100MG RMB370.40 In Stock
500MG RMB1138.40 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 219 °C
Boiling point: 466.6±45.0 °C(Predicted)
Density  1.343±0.06 g/cm3(Predicted)
refractive index  -33 ° (C=0.4, H2O)
storage temp.  under inert gas (nitrogen or Argon) at 2–8 °C
solubility  Soluble in DMSO (up to 2 mg/ml) or in Water (up to 2 mg/ml).
pka 2.21±0.23(Predicted)
form  crystalline
color  light yellow
optical activity -30.525 (H2O)
Merck  14,5328
Stability: Stable for 2 years as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 3 months.
InChIKey YGPSJZOEDVAXAB-QMMMGPOBSA-N

Description and Uses

Kynurenine (2922-83-0) is a tryptophan catabolite.1?Endogenous tumor-promoting ligand of the human aryl hydrocarbon receptor (AhR). Constitutively generated by human tumor cells via the action of the tryptophan degrading enzyme, tryptophan-2,3-dioxygenase (TDO). Kynurenine suppresses antitumor immune responses and promotes tumor cell survival and motility.2

L-Kynurenine has been used as a standard for indoleamine-2,3-dioxygenase (IDO) assay. It has also been used as a standard to extract and quantify kynurenine from cultured cells and media.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338
WGK Germany  3
RTECS  CY9049700
HS Code  2922500090

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