A7389512
(S)-(+)-2,2-Dimethyl-4-(hydroxymethyl)-1,3-dioxolane-p-toluenesulfonate , ≥97.0% , 23735-43-5
Synonym(s):
(S)-2,2-Dimethyl-1,3-dioxolane-4-methyl p-toluenesulfonate;L -α,β-Isopropylideneglycerol-γ-tosylate;2,3-Isopropylidene-sn-glycerol 1-tosylate;2,3-Isopropylidene-sn-glycerol 1-tosylate
Pack Size | Price | Stock | Quantity |
1G | RMB249.60 | In Stock |
|
5G | RMB804.00 | In Stock |
|
others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
Melting point: | 29-31 °C |
alpha | 4.2 º (c=10, abs.alcohol) |
Boiling point: | 398.71°C (rough estimate) |
Density | 1.208 g/mL at 25 °C(lit.) |
refractive index | n |
Flash point: | >230 °F |
storage temp. | Inert atmosphere,2-8°C |
form | powder to lump to clear liquid |
color | White or Colorless to Light yellow |
optical activity | [α]26/D +7.5°, c = 2% in DMF |
BRN | 89799 |
CAS DataBase Reference | 23735-43-5(CAS DataBase Reference) |
Description and Uses
(S)-(+)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-Toluenesulfonate has been used as a reactant for the synthesis of 16-(3-trifluoromethyl)phenoxy PGF2α analog travoprost (T715600) which has potent topical ocular activity. (S)-(+)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-Toluenesulfonate has also been used for the preparation of p38 mitogen activated protein (MAP) kinase inhibitors.
Safety
Symbol(GHS) | GHS07 |
Signal word | Warning |
Hazard statements | H315-H319-H335 |
Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P305+P351+P338 |
Hazard Codes | Xi |
Risk Statements | 36/37/38 |
Safety Statements | 26-36-37/39 |
WGK Germany | 3 |
F | 10-21 |
HS Code | 29329990 |