A7379712
Sulfasalazine , ≥98% , 599-79-1
Synonym(s):
2-Hydroxy-5-{{4-[(2-pyridinylamino)sulfonyl]phenyl}azo}benzoic acid;5-[4-(2-Pyridylsulfamoyl)phenylazo]salicylic acid;Salicylazosulfapyridine;Sulfasalazine
CAS NO.：599-79-1
Empirical Formula: C18H14N4O5S
Molecular Weight: 398.39
MDL number: MFCD00057363
EINECS: 209-974-3
| Pack Size | Price | Stock | Quantity |
| 5G | RMB39.20 | In Stock |
|
| 25G | RMB87.20 | In Stock |
|
| 100G | RMB295.20 | In Stock |
|
| 500g | RMB1279.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 260-265 °C (dec.)(lit.) |
| Boiling point: | 689.3±65.0 °C(Predicted) |
| Density | 1.3742 (rough estimate) |
| refractive index | 1.6000 (estimate) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | NH4OH 1 M: 50 mg/mL, clear, red |
| pka | pKa 0.6(H2O
t = 20
I < 0.001) (Uncertain);2.4(H2O
t = 20
I < 0.001) (Uncertain);9.7(H2O
t = 20
I < 0.001) (Uncertain);11.8(H2O
t = 20
I < 0.001) (Uncertain) |
| form | powder |
| color | Orange |
| Water Solubility | <0.1 g/100 mL at 25 ºC |
| Merck | 14,8942 |
| BRN | 356241 |
| BCS Class | 2,4 |
| Stability: | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month. |
| InChIKey | NCEXYHBECQHGNR-QZQOTICOSA-N |
| CAS DataBase Reference | 599-79-1(CAS DataBase Reference) |
| IARC | 2B (Vol. 108) 2016 |
| EPA Substance Registry System | Salicylazosulfapyridine (599-79-1) |
Description and Uses
Sulfasalazine (brand name Azulfidine in the U.S., Salazopyrin and Sulazine in Europe and Hong Kong) was developed in the 1950s specifically to treat rheumatoid arthritis. It was believed at the time that bacterial infections were the cause of rheumatoid arthritis. Sulfasalazine is a sulfa drug, (a derivative of mesalazine) and is formed by combining sulfa pyridine and salicylate with an azo bond. It may be abbreviated SSZ.
Sulfasalazine is an anti-inflammatory (gastrointestinal). Sulfasalazine has been used in granulomatous colitis.
Safety
| Symbol(GHS) |  GHS08 |
| Signal word | Danger |
| Hazard statements | H317-H334 |
| Precautionary statements | P261-P272-P280-P284-P302+P352-P333+P313 |
| Hazard Codes | Xn |
| Risk Statements | 42/43 |
| Safety Statements | 22-29/56-45 |
| RIDADR | 3077 |
| WGK Germany | 2 |
| RTECS | VO6250000 |
| F | 8 |
| HS Code | 29350090 |
| Hazardous Substances Data | 599-79-1(Hazardous Substances Data) |
| Toxicity | LD50 oral in rabbit: > 7500mg/kg |
