A7377112
Simvastatin , ≥97%(HPLC) , 79902-63-9
Synonym(s):
MK-733;MK-733, L-Type Calcium Channel Blocker VI;Simvastatin;Simvastatin - CAS 79902-63-9 - Calbiochem;SVA
CAS NO.：79902-63-9
Empirical Formula: C25H38O5
Molecular Weight: 418.57
MDL number: MFCD00072007
EINECS: 616-751-8
| Pack Size | Price | Stock | Quantity |
| 250MG | RMB24.80 | In Stock |
|
| 1G | RMB39.20 | In Stock |
|
| 5G | RMB86.40 | In Stock |
|
| 25G | RMB293.60 | In Stock |
|
| 100G | RMB979.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 127-132 °C (lit.) |
| alpha | D25 +292° (c = 0.5% in acetonitrile) |
| Boiling point: | 564.9±50.0 °C(Predicted) |
| Density | 1.11±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMSO: ≥20mg/mL |
| pka | 13.49±0.40(Predicted) |
| form | solid |
| color | white |
| optical activity | [α]/D +275±25°, c = 1 in acetonitrile |
| Merck | 14,8539 |
| BCS Class | 2 |
| Stability: | Stable for 2 years as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months. |
Description and Uses
Simvastatin is an once-daily hypolipemic, an analog of lovastatin indicated for the treatment of atherosclerosis. In patients with Type IN or IIB hypercholesterolemia, simvastatin reportedly produces significant reductions in total serum cholesterol, LDL, mglycerides and apolipoprotein-B, while HDL and apolipoprotein-A levels are increased.
A HMGCR inhibitor and anti-proliferative agent.
Safety
| Symbol(GHS) |  GHS08 |
| Signal word | Warning |
| Hazard statements | H361d |
| Precautionary statements | P201-P202-P280-P308+P313-P405-P501 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36-24/25 |
| WGK Germany | 2 |
| RTECS | EK7798000 |
| HS Code | 29322090 |
