Stigmasterol , >90.0% , 83-48-7

Synonym(s):
3β-Hydroxy-24-ethyl-5,22-cholestadiene;5,22-Stigmastadien-3β-ol;Stigmasterin;Stigmasterin; Phytosterol; beta-Stigmasterol; D5-Stigmasterol; 110801

CAS NO.：83-48-7

Empirical Formula: C29H48O

Molecular Weight: 412.7

MDL number: MFCD00003630

EINECS: 201-482-7

PRODUCT Properties

• Melting point: 165-167 °C (lit.)
• alpha: -50 º (c=2, CHCl3)
• Boiling point: 472.07°C (rough estimate)
• Density: 0.9639 (rough estimate)
• refractive index: 1.5000 (estimate)
• storage temp.: -20°C
• solubility: chloroform: soluble50 mg/ml
• form: Powder
• pka: 15.03±0.70(Predicted)
• color: White
• Water Solubility: insoluble
• λmax: 226nm(MeOH)(lit.)
• Merck: 14,8815
• BRN: 2568182
• LogP: 10.072 (est)

Description and Uses

Stigmasterol is a natural plant sterol that can be isolated from certain seed oils and herbs, including those used for therapeutic purposes. Dietary consumption of phytosterols, including stigmasterol, may have beneficial health effects in adults, particularly against cancer and ulceration. Alternatively, phytosterols may contribute to inflammation and intestinal failure-associated liver disease in young individuals.

Stigmasterol has been used as a phytosterol compound to test its anti-proliferative property in breast cancer cell culture and its effect on liver X receptor-α (LXRA) activation. It may be used as an internal standard for the quantification of yeast cell wall sterols using gas chromatography–mass spectrometry (GC-MS) analysis, and in the preparation of lipid monolayers.

Safety

• Symbol(GHS): GHS06,GHS08
• Signal word: Danger
• Hazard statements: H302-H315-H319-H331-H336-H351-H361d-H372-H412
• Precautionary statements: P201-P273-P301+P312+P330-P302+P352-P304+P340+P311-P308+P313
• Hazard Codes: Xn,Xi
• Risk Statements: 22-38-40-48/20/22-36/37/38-67-36/38-20-63
• Safety Statements: 22-24/25-36/37-36-26
• RIDADR: UN 1888 6.1/PG 3
• WGK Germany: 3
• RTECS: WJ2447500
• HS Code: 29309070