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A7282812

Sulfamethoxazole , Analysis standard product, 99% , 723-46-6

Synonym(s):
N1-(5-Methylisoxazol-3-yl)sulfanilamide;4-Amino-N-(5-methyl-3-isoxazolyl)benzenesulfonamide

CAS NO.:723-46-6

Empirical Formula: C10H11N3O3S

Molecular Weight: 253.28

MDL number: MFCD00010546

EINECS: 211-963-3

Pack Size Price Stock Quantity
250MG RMB230.40 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 166 °C
Boiling point: 482℃
Density  1.3915 (rough estimate)
refractive index  1.6630 (estimate)
Flash point: >110°(230°F)
storage temp.  Keep in dark place,Inert atmosphere,Room temperature
solubility  Practically insoluble in water, freely soluble in acetone, sparingly soluble in ethanol (96 per cent). It dissolves in dilute solutions of sodium hydroxide and in dilute acids.
form  Solid
pka pKa 5.60±0.05 (Uncertain)
color  White to Pale Yellow
Water Solubility  Soluble in ethanol or acetone. Very slightly soluble in water
Sensitive  Light Sensitive
Merck  14,8918
BRN  6732984
BCS Class 2,4
Stability: Stable, but light sensitive. Incompatible with strong oxidizing agents.
InChIKey JLKIGFTWXXRPMT-UHFFFAOYSA-N

Description and Uses

Like sulfisoxazole, this drug is effective in treating infections caused by streptococci, gonococci, pneumococci, staphylococci as well as colon bacillus. Unlike sulfisoxazole, only about 70% of it binds with proteins in the plasma after oral administration, and it diffuses mostly to tissues and tissue fluids. However, since it is removed much slower than sulfisoxazole, it does not require frequent administration and is also the drug of choice for many systemic infections. Moreover, it is an ingredient of a combined drug named bactrim, biseptol, and so on (which will be examined later on), which has a fixed correlation with trimethoprim. Synonyms of this drug are gantanol, sinomin, sulfisomezole, and others.

An antibacterial drug. Sulfonamide antibiotic that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase.This compound is a contaminant of emerging concern (CECs).

Safety

Symbol(GHS) 
GHS07,GHS08
Signal word  Warning
Hazard statements  H317-H361d
Precautionary statements  P201-P280-P302+P352-P308+P313
Hazard Codes  Xi,Xn
Risk Statements  36/37/38-43-22
Safety Statements  26-36-36/37/39-22
WGK Germany  2
RTECS  WP0700000
TSCA  Yes
HazardClass  IRRITANT
HS Code  29350090
Toxicity LD50 orally in mice: 3662 mg/kg (Yamamoto)

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