(<i>R</i>)-(-)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl <i>p</i>-Toluenesulfonate , >98.0%(GC) , 23788-74-1

Synonym(s):
D-α,β-Isopropylideneglycerol-γ-tosylate;1,2-Isopropylidene-sn-glycerol 3-tosylate

CAS NO.：23788-74-1

Empirical Formula: C13H18O5S

Molecular Weight: 286.34

MDL number: MFCD00063233

PRODUCT Properties

• Melting point: 41-43 °C(lit.)
• Boiling point: 398.71°C (rough estimate)
• Density: 1.208 g/mL at 25 °C(lit.)
• refractive index: n20/D 1.506(lit.)
• Flash point: >230 °F
• storage temp.: -20°C
• solubility: Dichloromethane; Chloroform; Ethyl Acetate; Methanol; DMF
• form: Oil
• color: Pale Brown
• optical activity: [α]/D 7.0±0.5°, neat
• BRN: 89800
• InChIKey: SRKDUHUULIWXFT-LLVKDONJSA-N
• CAS DataBase Reference: 23788-74-1(CAS DataBase Reference)

Description and Uses

(R)-(-)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-Toluenesulfonate is a chiral building block. It is used to prepare the antifungal agent ketoconazole. It is also used to prepare acyclic Nucleotide Analogs Derived from 8-Azapurines with antiviral activities.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319
• Precautionary statements: P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
• Hazard Codes: Xi,Xn
• Risk Statements: 36/37/38-22
• Safety Statements: 26-36-37/39
• WGK Germany: 3
• F: 10-21
• HS Code: 29329900