Rhapontigenin , >96.0% , 500-65-2

CAS NO.：500-65-2

Empirical Formula: C15H14O4

Molecular Weight: 258.27

MDL number: MFCD00017718

EINECS: 1312995-182-4

PRODUCT Properties

• Melting point: 189.0 to 193.0 °C
• Boiling point: 503.6±38.0 °C(Predicted)
• Density: 1.345±0.06 g/cm3(Predicted)
• storage temp.: 4°C, protect from light
• solubility: ≤30mg/ml in ethanol;30mg/ml in DMSO;30mg/ml in dimethyl formamide
• pka: 9.17±0.10(Predicted)
• form: powder to crystal
• color: White to Light yellow

Description and Uses

Rhapontigenin is a natural analog of resveratrol with antioxidant and anti-cancer activity. It is a mechanism-based, selective inactivator of cytochrome P450 1A1 (IC₅₀ = 400 nM), an aryl hydrocarbon hydroxylase which activates polycyclic aromatic hydrocarbons that act as procarcinogens. At higher concentrations, rhapontigenin inhibits the proliferation of HepG2 and HL-60R cancer cell lines (IC₅₀ = 48 μM).

Rhapontigenin is a natural analog of resveratrol and an inhibitor of CYP1A1.

Safety

• HS Code: 2914.50.3000