(R)-1,2,3,4-Tetrahydro-3-isoquinolinecarboxylic acid , 98% , 103733-65-9

CAS NO.：103733-65-9

Empirical Formula: C10H11NO2

Molecular Weight: 177.2

MDL number: MFCD00144038

EINECS: 266-580-4

PRODUCT Properties

• Melting point: 320-323 °C (decomp)
• Boiling point: 372.0±42.0 °C(Predicted)
• Density: 1.225±0.06 g/cm3(Predicted)
• storage temp.: Keep in dark place,Inert atmosphere,Room temperature
• solubility: Aqueous Acid (Slightly), Aqueous Base (Sparingly, Sonicated)
• pka: 2.21±0.20(Predicted)
• form: Crystalline Powder
• color: White
• InChI: InChI=1S/C10H11NO2/c12-10(13)9-5-7-3-1-2-4-8(7)6-11-9/h1-4,9,11H,5-6H2,(H,12,13)/t9-/m1/s1
• InChIKey: BWKMGYQJPOAASG-SECBINFHSA-N
• SMILES: C1C2=C(C=CC=C2)C[C@H](C(O)=O)N1
• CAS DataBase Reference: 103733-65-9(CAS DataBase Reference)

Description and Uses

D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid ((3R)-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid) is a magnetic, neutral compound. It is used as a pharmacological study to investigate the reaction mechanism and kinetics of the deuteration process. The asymmetric synthesis of D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid has been investigated using vinylene chloride and hydantoin as reactants. There are various parameters that affect the kinetics of this reaction such as solvent type and temperature. The nitric oxide synthase inhibitor activity of D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid has been studied in vitro. Results have shown that it inhibits nitric oxide synthase by binding to the heme iron of the enzyme and preventing the conversion of arginine

(R)-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic Acid, is an amino acid building block used in peptide synthesis. With a growing peptide drug market the fast, reliable synthesis of peptides is of great importance.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302-H315-H319-H335
• Precautionary statements: P261-P280-P301+P312-P302+P352-P305+P351+P338
• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• HS Code: 29334900