Home Categories Biochemical Engineering (R)-(-)-3-Amino-1-Boc-piperidine
A7122712

(R)-(-)-3-Amino-1-Boc-piperidine , 98% , 188111-79-7

Synonym(s):
(R)-1-Boc-3-piperidinamine;tert-Butyl (R)-3-amino-1-piperidinecarboxylate

CAS NO.:188111-79-7

Empirical Formula: C10H20N2O2

Molecular Weight: 200.28

MDL number: MFCD03094717

EINECS: 628-472-9

Pack Size Price Stock Quantity
1G RMB24.00 In Stock
5G RMB65.60 In Stock
25g RMB236.00 In Stock
100g RMB908.80 In Stock
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Update time: 2022-07-08

PRODUCT Properties

alpha  28.5 º (c=1, DMF)
Boiling point: 277.3±33.0 °C(Predicted)
Density  1.041±0.06 g/cm3(Predicted)
refractive index  1.4730
storage temp.  Keep in dark place,Inert atmosphere,2-8°C
solubility  Chloroform (Slightly), DMF (Slightly), DMSO (Slightly)
pka 10.35±0.20(Predicted)
form  Liquid
color  Colorless to pale yellow
optical activity [α]/D -28.5±2°, c = 1 in DMF
Water Solubility  Immiscible with water.
Sensitive  Moisture Sensitive
InChI InChI=1S/C10H20N2O2/c1-10(2,3)14-9(13)12-6-4-5-8(11)7-12/h8H,4-7,11H2,1-3H3/t8-/m1/s1
InChIKey AKQXKEBCONUWCL-MRVPVSSYSA-N
SMILES N1(C(OC(C)(C)C)=O)CCC[C@@H](N)C1
CAS DataBase Reference 188111-79-7(CAS DataBase Reference)

Description and Uses

(R)-3-Amino-1-Boc-piperidine can be used to prepare a benzoxazepine derivative named (R)-7-(3,5-dimethoxyphenyl)-N-(piperidin-3-yl)-4-propionyl-2,3,4,5-tetrahydro-1,4-benzoxazepine-9-carboxamide, a potent CBP/P300 bromodomain inhibitor.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P264-P270-P301+P312-P302+P352-P305+P351+P338
Hazard Codes  Xn
Risk Statements  22-36/37/38
Safety Statements  26
RIDADR  UN2735
WGK Germany  3
10-34
HazardClass  8
PackingGroup  III
HS Code  29333990

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