(R)-(-)-3-Amino-1-Boc-piperidine , 98% , 188111-79-7

Synonym(s):
(R)-1-Boc-3-piperidinamine;tert-Butyl (R)-3-amino-1-piperidinecarboxylate

CAS NO.：188111-79-7

Empirical Formula: C10H20N2O2

Molecular Weight: 200.28

MDL number: MFCD03094717

EINECS: 628-472-9

PRODUCT Properties

• alpha: 28.5 º (c=1, DMF)
• Boiling point: 277.3±33.0 °C(Predicted)
• Density: 1.041±0.06 g/cm3(Predicted)
• refractive index: 1.4730
• storage temp.: Keep in dark place,Inert atmosphere,2-8°C
• solubility: Chloroform (Slightly), DMF (Slightly), DMSO (Slightly)
• pka: 10.35±0.20(Predicted)
• form: Liquid
• color: Colorless to pale yellow
• optical activity: [α]/D -28.5±2°, c = 1 in DMF
• Water Solubility: Immiscible with water.
• Sensitive: Moisture Sensitive
• InChI: InChI=1S/C10H20N2O2/c1-10(2,3)14-9(13)12-6-4-5-8(11)7-12/h8H,4-7,11H2,1-3H3/t8-/m1/s1
• InChIKey: AKQXKEBCONUWCL-MRVPVSSYSA-N
• SMILES: N1(C(OC(C)(C)C)=O)CCC[C@@H](N)C1

Description and Uses

(R)-3-Amino-1-Boc-piperidine can be used to prepare a benzoxazepine derivative named (R)-7-(3,5-dimethoxyphenyl)-N-(piperidin-3-yl)-4-propionyl-2,3,4,5-tetrahydro-1,4-benzoxazepine-9-carboxamide, a potent CBP/P300 bromodomain inhibitor.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302-H315-H319-H335
• Precautionary statements: P261-P264-P270-P301+P312-P302+P352-P305+P351+P338
• Hazard Codes: Xn
• Risk Statements: 22-36/37/38
• Safety Statements: 26
• RIDADR: UN2735
• WGK Germany: 3
• F: 10-34
• HazardClass: 8
• PackingGroup: III
• HS Code: 29333990