Home Categories Biochemical Engineering Rotenone
A7114512

Rotenone , 95% , 83-79-4

Synonym(s):
Rotenone - CAS 83-79-4 - Calbiochem

CAS NO.:83-79-4

Empirical Formula: C23H22O6

Molecular Weight: 394.42

MDL number: MFCD09025614

EINECS: 201-501-9

Pack Size Price Stock Quantity
1G RMB85.60 In Stock
5G RMB332.00 In Stock
25G RMB1225.60 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 159-164 °C (lit.)
Boiling point: 210-220 °C/0.5 mmHg (lit.)
alpha  -115 º (C=1.4 IN CHLOROFORM)
Density  1.1917 (rough estimate)
refractive index  1.4593 (estimate)
storage temp.  Keep in dark place,Inert atmosphere,Room temperature
solubility  insoluble in EtOH; insoluble in H2O; ≥77.6 mg/mL in DMSO
form  White to off-white solid
Water Solubility  15 mg l-1 (100 °C)
color  White to Light yellow to Light orange
Merck  14,8271
BRN  6773081
Stability: Stable, but light and air sensitive. Combustible. Incompatible with oxidizing agents, especially in the presence of alkalies.
InChIKey JUVIOZPCNVVQFO-HBGVWJBISA-N

Description and Uses

The principal source of rotenone is the tuber root of Derris elliptica; however, it is also extracted from the roots of Derris mallaccensis, Lonchocarpus utilis, and Lonchocarpus uruca. Rotenone is both a stomach and contact poison for arthropods. Its fast knockdown action is attributed to decreasing the availability of nicotinamide adenine dinucleotide to serve as a cofactor in various biochemical pathways including the Krebs cycle, thereby inhibiting the mitochondrial respiratory enzymes.

Rotenone is an broad spectrum insecticide that occurs naturally in seeds and stems of several plants. Rotenone was first registered in 1947 and is currently used exclusively to kill fish (U.S. EPA, 2007). In 2006, registrants voluntarily canceled all livestock, residential and home owner uses, domestic pet uses, and all other uses except for piscicide uses. Currently the main uses include fish management strategies to remove nonnative fish species from lakes, ponds, or streams and in catfish aquaculture prior to stocking ponds with with fry to remove undesirable fish species (U.S. EPA, 2006d).
Rotenone has been historically used by native people to paralyze fish for capture and consumption. Outside the United States, the compound is still used to control insects in fruit and vegetable cultivation and for control of fire ants and mosquito larvae in pond water (HSDB, 2012a).

Safety

Symbol(GHS) 
GHS06,GHS09
Signal word  Danger
Hazard statements  H300+H330-H315-H319-H335-H410
Precautionary statements  P260-P264-P273-P302+P352-P304+P340+P310-P305+P351+P338
Hazard Codes  T,N
Risk Statements  25-36/37/38-50/53
Safety Statements  22-24/25-36-45-60-61
RIDADR  UN 2811 6.1/PG 3
OEB B
OEL TWA: 5 mg/m3
WGK Germany  3
RTECS  DJ2800000
HazardClass  6.1(b)
PackingGroup  III
HS Code  29329990
Toxicity LD50 i.p. in mice: 2.8 mg/kg (Fukami); in rats (mg/kg): 132 orally; 6 i.v. (Soloway)
IDLA 2,500 mg/m3

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