β-D-Ribofuranose 1-acetate 2,3,5-tribenzoate , 98% , 6974-32-9

Synonym(s):
β-D-Ribofuranose 1-acetate 2,3,5-tribenzoate;1-O-Acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose;1-O-Acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose

CAS NO.：6974-32-9

Empirical Formula: C28H24O9

Molecular Weight: 504.48

MDL number: MFCD00005357

EINECS: 230-220-4

PRODUCT Properties

• Melting point: 128-130 °C
• alpha: 24.4 º (c=1, pyridine)
• Boiling point: 621.0±55.0 °C(Predicted)
• Density: 1.35±0.1 g/cm3(Predicted)
• refractive index: 24 ° (C=1, Pyridine)
• storage temp.: Sealed in dry,Room Temperature
• solubility: Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly, Sonicated),
• form: Liquid
• color: Clear slightly yellow or greenish to brown
• optical activity: [α]20/D +24.3°, c = 1 in pyridine
• BRN: 100243
• InChIKey: GCZABPLTDYVJMP-CBUXHAPBSA-N
• SMILES: C(OC)(=O)C1=CC=CC=C1[C@@H]1[C@@H](OC(=O)C2=CC=CC=C2)[C@@H](OC(=O)C2=CC=CC=C2)[C@H](OC(C)=O)O1 |&1:10,11,21,31,r|

Description and Uses

β-D-Ribofuranose 1-Acetate 2,3,5-Tribenzoate is an optically active ribose derivative. It is white to orange to green powder to crystals, slightly soluble in methanol, and can be used as a starting material for nucleoside synthesis. The substance is also used as an intermediate for Clofarabine, which belongs to a class of drugs called purine nucleoside antimetabolites and is used to treat acute lymphoblastic leukemia (ALL) in children and young adults aged 1 to 21 years.

An inhibitor of neutrophil-keyhole limpet hemocyanin adhesion

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P305+P351+P338
• Hazard Codes: Xi
• Risk Statements: 36/38
• Safety Statements: 22-24/25-37/39-26
• WGK Germany: 3
• TSCA: Yes
• HS Code: 29400090