2'-Deoxyadenosinemonohydrate , 10mMinDMSO , 16373-93-6
Synonym(s):
9-(2-Deoxy-β-D -ribofuranosyl)adenine;Adenine deoxyriboside
CAS NO.:16373-93-6
Empirical Formula: C10H15N5O4
Molecular Weight: 269.26
MDL number: MFCD00149364
EINECS: 683-408-7
Pack Size | Price | Stock | Quantity |
1ml | RMB159.20 | In Stock |
|
others | Enquire |
PRODUCT Properties
Melting point: | 187-189 °C |
refractive index | -25.5 ° (C=0.5, H2O) |
storage temp. | 2-8°C |
solubility | H2O: soluble50mg/mL, clear, colorless |
form | powder |
color | White to light beige |
Water Solubility | 0.3 g/100 mL (20 ºC) |
BRN | 5191174 |
Stability: | Stable, but air sensitive. Incompatible with strong oxidizing agents. |
InChIKey | WZJWHIMNXWKNTO-VWZUFWLJSA-N |
CAS DataBase Reference | 16373-93-6(CAS DataBase Reference) |
Description and Uses
2'-Deoxyadenosine monohydrate is an adenosine nucleotide, which can be synthesized by the enzyme adenosine kinase. 2'-Deoxyadenosine monohydrate is a competitive inhibitor of phosphodiesterase, which breaks down cyclic nucleotides to their corresponding monophosphate form. This leads to elevated levels of cAMP, which can cause neuronal death by apoptosis.
2'-Deoxyadenosineise is used by some cells as an energy source under energy stress conditions and to affect cAMP levels. 2'-dAdo is used in comparison studies of the functions of adenosine analogues on various biological processes.
Safety
Symbol(GHS) | GHS07 |
Signal word | Warning |
Hazard statements | H302 |
Precautionary statements | P264b-P270-P301+P312-P330-P403-P501c |
Hazard Codes | Xn,Xi |
Risk Statements | 22-36/37/38-20/21/22 |
Safety Statements | 24/25-37/39-36-26 |
RIDADR | UN2811 6.1/PG 3 |
WGK Germany | 3 |
RTECS | AU7358600 |
F | 10-23 |
TSCA | Yes |
HS Code | 29349990 |